中成药2024，Vol.46Issue(8)：2601-2605,5.DOI:10.3969/j.issn.1001-1528.2024.08.017
补肾祛瘀汤联合常规治疗对肾虚血瘀型绝经后骨质疏松症患者的临床疗效
Clinical effects of Bushen Quyu Decoction combined with conventional treatment on patients with postmenopausal osteoporosis due to Kidney Deficiency and Blood Stasis
摘要
Abstract
AIM To investigate the clinical effects of Bushen Quyu Decoction combined with conventional treatment on patients with postmenopausal osteoporosis due to Kidney Deficiency and Blood Stasis.METHODS One hundred and six patients were randomly assigned into control group(53 cases)for 6-month intervention of conventional treatment,and observation group(53 cases)for 6-month intervention of both Bushen Quyu Decoction and conventional treatment.The changes in clinical effects,TCM syndrome scores,bone metabolism indices(β-CTX,PINP,BGP),bone mineral density,oxidative stress indices(SOD,AOPP,MAOA)and incidence of adverse reactions were detected.RESULTS The observation group demonstrated higher total effective rate than the control group(P＜0.05).After the treatment,the two groups displayed decreased TCM syndrome scores,β-CTX,BGP,AOPP,MAOA(P＜0.05),and increased PINP,bone mineral density,SOD(P＜0.05),especially for the observation group(P＜0.05).No significant difference in incidence of adverse reactions was found between the two groups(P＞0.05).CONCLUSION For the patients with postmenopausal osteoporosis due to Kidney Deficiency and Blood Stasis,Bushen Quyu Decoction combined with conventional treatment can safely and effectively improve bone mineral density,bone metabolism indices,and alleviate oxidative stress responses.关键词
补肾祛瘀汤/常规治疗/绝经后骨质疏松症/肾虚血瘀Key words
Bushen Quyu Decoction/conventional treatment/postmenopausal osteoporosis/Kidney Deficiency and Blood Stasis分类
医药卫生引用本文复制引用
肖丽,谢菊英,刘韵,胡丽萍,曹夏,石峻林..补肾祛瘀汤联合常规治疗对肾虚血瘀型绝经后骨质疏松症患者的临床疗效[J].中成药,2024,46(8):2601-2605,5.基金项目
湖南创新型省份建设专项(2022JJ70124) （2022JJ70124）
2020 年湘南学院国自重点培育项目(2020XJ09) （2020XJ09）
