中外医学研究2024，Vol.22Issue(21)：5-8,4.DOI:10.14033/j.cnki.cfmr.2024.21.002
帕金森患者定量脑电图、血压变异性变化及其与认知功能的相关性分析
Analysis of Quantitative EEG and Blood Pressure Variability Changes and their Correlation with Cognitive Function in Parkinson's Patients
陈静 1陈泽鹏 1江沛 1张强 2周敬华 2周华军2
作者信息
- 1. 宜都市人民医院 湖北 宜都 443300
- 2. 三峡大学第一临床医学院(宜昌市中心人民医院)
- 折叠
摘要
Abstract
Objective:To analyze changes in quantitative EEG and blood pressure variability and their correlation with cognitive function in Parkinson's patients.Method:88 Parkinson's patients admitted to Yidu People's Hospital from June 2022 to October 2023 were selected as study subjects.Their cognitive functions were scored by using the Brief Mental State Exercise Scale(MMSE),and according to the scoring results,they were categorized into the cognitively impaired group(35 cases)and the non-cognitively impaired group(53 cases).The Parkinson's Disease Rating Scale(UPDRS)was used to compare the mental status,activities of daily living,motor examination,and motor complications between the two groups.Quantitative EEG(frontal,central,temporal,parietal,occipital)power spectrum coefficient and blood pressure variability(24 h mean systolic blood pressure and its standard deviation,24 h mean diastolic blood pressure and its standard deviation)were compared between the two groups.Correlations among quantitative EEG power spectral ratios,changes in blood pressure variability,and cognitive function were analyzed by using Person.Result:There was no statistically significant difference in the UPDRS scores of the two groups(P>0.05).The frontal,central,temporal,parietal,and occipital regions of patients in the cognitive impairment group were lower than those in the non-cognitive impairment group,and the difference was statistically significant(P<0.05).The result of person analysis showed that both quantitative EEG power spectral ratios and blood pressure variability correlated with cognitive function in Parkinson's patients.Conclusion:Both quantitative brainwave power ratio and blood pressure variability in Parkinson's patients who developed cognitive impairment were significantly different from those in Parkinson's patients who did not develop cognitive impairment,and there was a significant correlation between the above metrics and cognitive function in Parkinson's patients.关键词
帕金森/定量脑电图/血压变异性/认知功能/相关性Key words
Parkinson's disease/Quantitative electroencephalogram/Blood pressure variabi/Cognitive function/Relevance引用本文复制引用
陈静,陈泽鹏,江沛,张强,周敬华,周华军..帕金森患者定量脑电图、血压变异性变化及其与认知功能的相关性分析[J].中外医学研究,2024,22(21):5-8,4.
