PCNL对复杂型肾结石患者结石清除情况、手术相关指标及并发症的影响分析OA
Analysis of the Effect of PCNL on Stone Clearance,Surgery-related Indexes and Complications in Patients with Complex Renal Stones
目的:分析经皮肾镜取石术(PCNL)对复杂型肾结石患者结石清除情况、手术相关指标及并发症的影响.方法:选取 2023 年 1-12 月咸宁市第一人民医院收治的 80 例复杂型肾结石患者作为研究对象,按数字随机分组法分为试验组和对照组,每组各 40 例.对照组患者采用输尿管软镜下钬激光碎石术治疗,试验组患者采用PCNL治疗.对比两组患者手术相关指标[碎石时间、血红蛋白(HB)水平下降值、术中出血量、住院时间]、并发症(血尿、尿瘘、发热、尿路感染、肾周损伤)发生率、一期结石清除率、二期手术率以及炎症水平、肾功能水平改善情况.结果:两组患者碎石时间比较,差异无统计学意义(P>0.05).试验组患者住院时间短于对照组,差异有统计学意义(P<0.05).试验组患者Hb水平下降值、术中出血量低于对照组,差异有统计学意义(P<0.05).手术后,试验组患者各项炎症指标、肾功能水平均低于对照组,差异有统计学意义(P<0.05).试验组患者术后血尿、尿瘘、发热、尿路感染、肾周损伤等并发症发生率均低于对照组,差异有统计学意义(P<0.05).试验组一期结石清除率高于对照组,二期手术率低于对照组,差异有统计学意义(P<0.05).结论:PCNL能有效提高复杂型肾结石患者结石清除率,有利于降低术中出血量和并发症发生率,缩短患者住院时间,促进患者炎症水平和肾功能水平改善.
Objective:To analyze the effect of percutaneous nephrolithotomy(PCNL)on stone clearance,surgery-related indices,and complications in patients with complex renal stones.Method:80 patients with complex kidney stones admitted to the First People's Hospital of Xianning City from January to December 2023 were selected as the study subjects,and were divided into the experimental group and the control group according to the method of numerical randomization grouping,with 40 cases in each group.Patients in the control group were treated with holmium laser lithotripsy under flexible ureteroscopy,and patients in the test group were treated with PCNL.The surgery-related indexes[lithotripsy time,decreased value of hemoglobin(HB)level,intraoperative bleeding,hospitalization time],complication(hematuria,urinary fistula,fever,urinary tract infection,perirenal injury)incidence,phase Ⅰ stone removal rate,phase Ⅱ surgery rate,as well as improvement of inflammation level and renal function level,were compared between the two groups of patients.Result:The difference in lithotripsy time between the two groups was not statistically significant(P>0.05).The hospitalization time of patients in the test group was shorter than that of the control group,and the difference was statistically significant(P<0.05).The value of decrease in Hb level and intraoperative bleeding of patients in the test group was lower than that of the control group,and the difference was statistically significant(P<0.05).After surgery,all inflammatory indicators and renal function levels of patients in the test group were lower than those of the control group,and the difference was statistically significant(P<0.05).The complication rates of postoperative hematuria,urinary fistula,fever,urinary tract infection and perinephric injury of patients in the test group were lower than those of the control group,and the difference was statistically significant(P<0.05).The rate of one-stage stone removal in the test group was higher than that in the control group,and the rate of second-stage surgery was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:PCNL can effectively improve the stone removal rate of patients with complex renal stones,which is conducive to reducing the amount of intraoperative bleeding and the incidence of complications,shortening the hospitalization time of patients,and promoting the improvement of patients'inflammation level and renal function level.
胡捷
咸宁市第一人民医院 湖北 咸宁 437000
经皮肾镜取石术复杂型肾结石结石清除手术指标并发症影响
Percutaneous nephrolithotomyComplex kidney stonesStone removalSurgical indexComplicationsEffect
《中外医学研究》 2024 (021)
17-20 / 4
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