中外医学研究2024，Vol.22Issue(21)：29-32,4.DOI:10.14033/j.cnki.cfmr.2024.21.008
腹腔镜下低位直肠癌保肛术对老年低位直肠癌患者疼痛因子、应激反应指标及肠道功能的影响
The Effect of Laparoscopic Sphincter Preservation Surgery on Pain Factors,Stress Response Indicators and Intestinal Function in Elderly Patients with Low Rectal Cancer
李挺 1罗炜 1杨朋来2
作者信息
- 1. 枣庄市立医院 山东 枣庄 277100
- 2. 枣庄市中医医院
- 折叠
摘要
Abstract
Objective:To observe the effects of laparoscopic sphincter preservation surgery on pain factors,stress response indicators,and intestinal function in elderly patients with low rectal cancer.Method:100 elderly patients with low rectal cancer in Zaozhuang Municipal Hospital from January 2022 to January 2023 were randomly divided into two groups using a number table.50 cases in the control group were treated with traditional combined abdominal and perineal resection,while 50 cases in the observation group were treated with laparoscopic sphincter preservation surgery for low rectal cancer.The pain factors,stress response indicators,and intestinal function were compared between two groups.Result:The neuropeptide(NPY)and prostaglandin E2(PGE2)levels in the observation group were lower than those in the control group the first day after surgery,the differences were statistically significant(P<0.05)while cortisol(Cor),aldosterone(ALD),and propylene glycol(MDA)levels were lower than those in the control group the first day after surgery.The maximum tolerable volume(MTV),maximum systolic pressure(MSP),and resting pressure(ARP)of the anal canal in the observation group were higher than those in the control group the third month after surgery.The Memorial Sloan Kettering Cancer Center(MSKCC)Intestinal Function Questionnaire The quality of life scale(EORTC QLQ-C30)score of cancer patients was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion:Laparoscopic sphincter preservation surgery for low rectal cancer has a regulatory effect on pain factors and stress response indicators in elderly patients with low rectal cancer,which can promote postoperative recovery of intestinal function and improve the living quality.关键词
低位直肠癌/腹腔镜下低位直肠癌保肛术/疼痛因子/应激反应/肠道功能Key words
Low rectal cancer/Laparoscopic sphincter preservation surgery for low rectal cancer/Pain factors/Stress response/Intestinal function引用本文复制引用
李挺,罗炜,杨朋来..腹腔镜下低位直肠癌保肛术对老年低位直肠癌患者疼痛因子、应激反应指标及肠道功能的影响[J].中外医学研究,2024,22(21):29-32,4.
