miR-21-5p靶向BNC2调控食管癌的恶性生物行为的研究OA北大核心CSTPCD
Research on how miR-21-5p targets BNC2 to control the malignant biological activity of esophageal cancer
目的:探讨miR-21-5p靶向肌成纤维细胞的身份转录因子(BNC2)调控食管癌(esophageal cancer,ESCA)细胞增殖、迁移、侵袭机制.方法:应用实时定量PCR(real-time quantitative polymerase chain reaction,qRT-PCR)方法检测食管癌组织中miR-21-5P和BNC2的相对表达量并用统计学分析其是否存在表达差异.用miR-21-5p mimics和miR-21-5P inh…查看全部>>
Objective:To investigate the mechanism by which the identity transcription factor(BNC2)of myoblasts targeted by miR-21-5p in controling the proliferation,migration,and invasion of esophageal cancer(ESCA)cells.Methods:Real-time quantitative polymerase chain reaction(qRT-PCR)was used to assess the relative expression levels of miR-21-5P and BNC2 in esophageal cancer tissues.And any differences in expression were statistically analyzed.Following transfection of…查看全部>>
邓雨函;阳梦;吴振华;李卉;热则耶·麦麦提祖农;孙晓宏
新疆医科大学附属肿瘤医院,新疆 乌鲁木齐 830011新疆医科大学附属肿瘤医院,新疆 乌鲁木齐 830011新疆医科大学附属肿瘤医院,新疆 乌鲁木齐 830011新疆医科大学中心实验室,新疆 乌鲁木齐 830011新疆医科大学基础医学院,新疆 乌鲁木齐 830011新疆医科大学附属肿瘤医院,新疆 乌鲁木齐 830011
临床医学
食管癌miR-21-5PBNC2预后肿瘤微环境
Tumor microenvironmentBNC2MiR-21-5PEsophageal cancerPrognosis
《海南医学院学报》 2024 (16)
1236-1245,10
This study was supported by Xinjiang Uygur Autonomous Region Natural Science Foundation General Project(2016D01C3692021D01C397) 新疆维吾尔自治区自然科学基金面上项目(2016D01C369,2021D01C397)
评论