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甲状旁腺全切联合前臂自体移植术在三发性甲状旁腺功能亢进症中的应用价值分析

罗晓敏 史红霞 郭芳 宋银平 张俊杰

哈尔滨医药2024,Vol.44Issue(4):12-15,4.
哈尔滨医药2024,Vol.44Issue(4):12-15,4.DOI:10.3969/j.issn.1001-8131.2024.04.004

甲状旁腺全切联合前臂自体移植术在三发性甲状旁腺功能亢进症中的应用价值分析

Analysis of the Application Value of Total Parathyroidectomy Combined with Forearm Autotransplantation in Triple Essential Hyperparathyroidism

罗晓敏 1史红霞 1郭芳 1宋银平 1张俊杰1

作者信息

  • 1. 河南中医药大学第五临床医学院(郑州人民医院),河南 郑州 450000
  • 折叠

摘要

Abstract

Objective Exploring the value of total parathyroidectomy combined with forearm autotransplantation in the treatment of triple hyperparathyroidism.Method 144 patients with triple essential hyperparathyroidism were randomLy divided into a control group and a study group,with 72 cases in each group.The control group underwent total parathyroidectomy for treatment,while the study group underwent forearm autologous transplantation on the basis of the control group.The biochemical indicators,quality of life,HGB,ALB levels,symptom scores,and clinical efficacy of the two groups of patients were compared.Result After treatment,the patients in the study had lower levels of iPTH,Ca,P,Mg,bone pain VAS,pruritus VAS and sleep SRSS than the control group(P<0.05).Af-ter treatment,the patients in the study had higher levels of ALP,quality of life and treatment efficacy than the control group(P<0.05).Conclusion In patients with triple hyperparathyroidism,the combination of total parathyroidectomy and forearm autograft showed good clinical efficacy,which not only significantly improved the patients'biochemical indicators,but also their quality of life.

关键词

三发性甲状旁腺功能亢进症/甲状旁腺全切/前臂自体移植术/生化指标

Key words

Tertiary hyperparathyroidism/Total parathyroidectomy/Forearm autotransplantation/Biochemical indicators

分类

医药卫生

引用本文复制引用

罗晓敏,史红霞,郭芳,宋银平,张俊杰..甲状旁腺全切联合前臂自体移植术在三发性甲状旁腺功能亢进症中的应用价值分析[J].哈尔滨医药,2024,44(4):12-15,4.

基金项目

河南省医学科技攻关计划联合共建项目(2018020827) (2018020827)

哈尔滨医药

1001-8131

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