基础医学与临床2024，Vol.44Issue(9)：1202-1207,6.DOI:10.16352/j.issn.1001-6325.2024.09.1202
器官芯片——更具前景的体外模型
Organ-on-a-chip:a more promising in vitro model
摘要
Abstract
Traditional in vitro models have inevitable limitations and there are significant differences in assessing drug efficacy and side effects as compared to human trials.Organ-on-a-chip technology simulates human organs in a physiological environment and functional chip with a high fidelity physiological or pathophysiological level,offering great innovative prospects for drug development.This paper mainly introduces the research progress and application of organ chip from the perspective of various systems in vivo.At the same time,the limitations of the current devel-opment process of organ chip and the future development direction are proposed.关键词
器官芯片/类器官/疾病模型Key words
organ-on-a-chip/organoid/disease model分类
基础医学引用本文复制引用
杨振丽,夏雨佳,刘玉琴..器官芯片——更具前景的体外模型[J].基础医学与临床,2024,44(9):1202-1207,6.基金项目
中国医学科学院医学与健康科技创新工程-重大协同创新项目(2021-I2M-1-053) （2021-I2M-1-053）
