检验医学与临床2024，Vol.21Issue(16)：2324-2327,2333,5.DOI:10.3969/j.issn.1672-9455.2024.16.005
GIDS在老年AECOPD呼吸衰竭患者病情及预后评估中的应用
Application of GIDS in the evaluation of disease severity and prognosis in elderly patients with AECOPD complicated with respiratory failure and its influence on prognosis
摘要
Abstract
Objective To explore the correlation between gastrointestinal dysfunction score(GIDS)and disease severity in elderly patients with acute exacerbation of chronic obstructive pulmonary disease(AECO-PD)complicated with respiratory failure and its predictive value for prognosis,in order to provide reference basis for evaluation of disease severity and prognosis.Methods A total of 264 elderly AECOPD patients com-plicated with respiratory failure treated in the ICU of the hospital from January 2020 to August 2023 were col-lected as study subjects.According to the patients'GIDS,the patients were divided into low GIDS score group(0-1 score)and high GIDS group(2-4 scores).Acute Physiology and Chronic Health Status Scoring Sys-tem Ⅱ(APACHE Ⅱ)scores and Sequential Organ Failure Assessment(SOFA)scores of patients in differ-ent levels of GIDS groups were compared,as well as indicators of patients'hospitalization outcomes,including duration of mechanical ventilation,duration of ICU stay and prognosis.Spearman's correlation was used to an-alyze the correlation between GIDS and APACHE Ⅱ score and SOFA score.The predictive value of GIDS for prognosis was analyzed by receiver operating characteristic(ROC)curve.Results The mean GIDS of 264 eld-erly AECOPD patients with respiratory failure was 2.00(1.00,3.00),including 53 cases of zero(20.1％),65 cases of 1 point(24.6％),53 cases of 2 points(20.1％),45 cases of 3 points(17.0％)and 48 cases of 4 points(18.2％).APACHE Ⅱ score and SOFA score in the high GIDS group were higher than those in the low GIDS group(P＜0.05).Correlation analysis results showed that GIDS was positively correlated with APACHE Ⅱscore and SOFA score(r=0.458,0.392,P＜0.05).The mechanical ventilation time and ICU stay time in the high GIDS group were longer than those in the low GIDS group,while the incidence of poor prognosis was higher than that in the low GIDS group,with statistically significant differences(P＜0.05).The area under the curve of GIDS for predicting poor prognosis was 0.823,with sensitivity of 93.4％and specificity of 60.1％.Conclusion GIDS in elderly AECOPD patients complicated with respiratory failure is closely related to disease severity,and it has good predictive value for poor prognosis.关键词
老年/慢阻肺急性加重期/呼吸衰竭/胃肠道功能障碍评分/疾病严重程度/预后Key words
elderly/acute exacerbation of chronic obstructive pulmonary disease/respiratory failure/gastrointestinal dysfunction score/disease severity/prognosis分类
医药卫生引用本文复制引用
刘艳,王红梅,卢晓丽,杨菊荣,赵娟,杨春波,付晓乐..GIDS在老年AECOPD呼吸衰竭患者病情及预后评估中的应用[J].检验医学与临床,2024,21(16):2324-2327,2333,5.基金项目
省部共建中亚高发病成因与防治国家重点实验室开放课题(SKL-HIDCA-2021-ZY13) （SKL-HIDCA-2021-ZY13）
新疆维吾尔自治区十三·五重点学科临床医学高峰学科新疆医科大学第一临临床医学院暨第一附属医院院内科研类课题(KYZD-03). （KYZD-03）
