日用化学品科学2024，Vol.47Issue(8)：42-46,5.DOI:10.3969/j.issn.1006-7264.2024.08.009
青蒿提取物舒缓与控油祛痘功效研究
Study on the soothing,oil control and anti-acne effects of Artemisia annua extract
袁道欢 1黄嘉敏 1林霁 1贺锐 2解勇2
作者信息
- 1. 植物医生(广东)生物科技有限公司,广东 佛山 528300
- 2. 北京植物医生生物科技有限公司,北京 100044
- 折叠
摘要
Abstract
Preliminary exploration of the soothing,oil control,and anti-acne effects and mechanisms of Artemisia annua extract were conducted in this study.The soothing effect of Artemisia annua extract was tested by hyaluronidase biochemical reaction.The soothing and oil-controlling effects of Artemisia annua extract were investigated by cell model.The inhibitory effect of Artemisia annua extract on propionibacterium acnes was studied by suspension quantitative method.Results showed that Artemisia annua extract could effectively inhibit the degradation of hyaluronic acid(P<0.01).Artemisia annua extract significantly inhibited the secretion of inflammatory cytokines TNF-α and IL-6 in RAW264.7 cells(P<0.05).Artemisia annua extract at 0.5%,0.25%,0.125%could significantly inhibit the secretion of oil by SZ95 cells(P<0.05).The minimum inhibitory concentration of Artemisia annua extract against propionibacterium acnes was 0.625%,and the inhibitory rate against propionibacterium acnes increased with the increase of the concentration of Artemisia annua extract.In summary,Artemisia annua extract can achieve anti-acne efficacy through soothing and oil control,and this function may be achieved by reducing hyaluronic acid degradation,inhibiting inflammatory pathways produced by inflammatory factors TNF-α and IL-6,inhibiting oil secretion,and inhibiting the growth of propionibacterium acnes.关键词
青蒿提取物/舒缓/细胞/控油/抑菌Key words
Artemisia annua extract/soothing/cells/oil control/antibacterial effect分类
化学化工引用本文复制引用
袁道欢,黄嘉敏,林霁,贺锐,解勇..青蒿提取物舒缓与控油祛痘功效研究[J].日用化学品科学,2024,47(8):42-46,5.
