四川精神卫生2024，Vol.37Issue(4)：376-378,3.DOI:10.11886/scjsws20240229002
盐酸度洛西汀治疗抑郁症引发抗利尿激素分泌紊乱综合征1例
Duloxetine hydrochloride induced syndrome of inappropriate antidiuretic hormone secretion in depression treatment:a case report
杨舒婷 1范阿娇2
作者信息
- 1. 兰州大学第一临床医学院,甘肃 兰州 730000
- 2. 兰州大学第二医院,甘肃 兰州 730030
- 折叠
摘要
Abstract
Duloxetine hydrochloride,a serotonin-norepinephrine reuptake inhibitor(SNRIs),is a commonly used antidepressants.Its mechanism of action involves increasing synaptic monoamine neurotransmitters concentration,leading to antidepressant effects.While gastrointestinal reactions and elevated blood pressure are common side effects,duloxetine can rarely induce syndrome of inappropriate antidiuretic hormone secretion(SIADH).This case report presents a patient with depression who developed SIADH following duloxetine hydrochloride initiation,with the main clinical manifestation being restless thirst and excessive drinking.This case is presented to raise awareness among clinicians of this rare yet potentially serious adverse effect of duloxetine treatment.关键词
盐酸度洛西汀/抑郁症/抗利尿激素分泌紊乱综合征Key words
Duloxetine hydrochloride/Depression/Syndrome of inappropriate antidiuretic hormone secretion分类
临床医学引用本文复制引用
杨舒婷,范阿娇..盐酸度洛西汀治疗抑郁症引发抗利尿激素分泌紊乱综合征1例[J].四川精神卫生,2024,37(4):376-378,3.
