中国伤残医学2024，Vol.32Issue(11)：17-22,6.DOI:10.13214/j.cnki.cjotadm.2024.011.005
病灶扩大切除结合膜诱导技术治疗成人下肢感染性骨缺损的影响因素分析
Analysis of Influential Factors in the Treatment of Infective Bone Defect in Adult Lower Extremities by Expanded Lesion Resection Combined with Membrane Induction
摘要
Abstract
Objective:To analyze the influencing factors of extended resection combined with induced membrane technique in the treatment of adult lower extremity infected bone defects.Methods:The clinical data of 40 patients with infectious bone defects of lower limb long bone treated in our hospital from May 2016 to March 2022 were retrospectively analyzed.All patients received extensive resection of the lesion combined with membrane induction technique after admission.The results of the two stages of surgical treatment were recorded in detail,and the related factors affecting the bone healing time and the improvement of lower limb function were analyzed.Results:The C-reactive protein,erythrocyte sedimentation rate,and white blood cell count of the patients 1 year after operation were lower than those before operation,and the scores of the short form health survey and the lower extremity Functional Evaluation scale(LEFS)were higher than those before operation,and the differences were statistically significant(P<0.05).The bone healing time was related to the age of the patients and the location of the lesion.The bone healing speed was slower in the older patients,and the healing speed of the femur was faster than that of the tibia,and the differences were statistically significant(P<0.05).There was no significant correlation with C-M classification,bone graft type,interval time,one-stage fixation method and etiology(P>0.05).The postoperative improvement of lower limb function(LEFS score)was related to the method of intraoperative fixation at the first stage,and internal fixation was more conducive to the improvement of lower limb function(P<0.05).There was no significant correlation with other factors(P>0.05).Conclusion:Extensive resection of the lesion combined with induction membrane technique is effective in the treatment of infectious bone defects in the long bone of the lower extremity,which has a good effect on the control of infection.The main factors affecting bone healing are age and lesion site.关键词
下肢长骨干感染性骨缺损/病灶扩大切除/膜诱导技术/感染率/治疗效果/影响因素Key words
Infectious bone defect of lower limb long bone/Extensive resection of the lesion/Membrane induction technology/The infection rate/The therapeutic effect/Influencing factors分类
医药卫生引用本文复制引用
李茂伦,张锋,王布雨,骆艳飞,阮世强..病灶扩大切除结合膜诱导技术治疗成人下肢感染性骨缺损的影响因素分析[J].中国伤残医学,2024,32(11):17-22,6.基金项目
贵州省科技计划项目(黔科合基础-ZK[2021]一般393) （黔科合基础-ZK[2021]一般393）
贵州省卫生健康委科学技术基金项目(gzwkj2021-259) （gzwkj2021-259）
贵州省科技计划项目(黔科合成果-LC[2022]029) （黔科合成果-LC[2022]029）
