实用医学杂志2024，Vol.40Issue(16)：2199-2205,7.DOI:10.3969/j.issn.1006-5725.2024.16.001
糖尿病分型新视野——基于临床表现向基于病因分子机制转变
A new vision of diabetes classification:A shift from clinical manifestation to etiological molecular mecha-nism
摘要
Abstract
The classification of diabetes is undergoing a significant transformation.As advancements in medical technology and a deeper understanding of its etiology,traditional classification methods based on clinical characteristics and insulin dependency are increasingly revealing their limitations.In recent years,the integration of genomic,epigenetic,and metabolomic technologies,combined with the application of big data analytics and machine learning in disease classification,has propelled diabetes classification towards enhanced precision and personalization.These cutting-edge technologies elucidate the intricate pathophysiological mechanisms and exten-sive heterogeneity inherent in diabetes,offering novel methodologies for early diagnosis,individualized treatment,and prognostic evaluation.This paradigm shift not only deepens the comprehension of diabetes complexity but also holds the potential to provide more precise and efficacious therapeutic interventions for patients.Consequently,this marks a historic transition from simplistic,clinically-based classification systems to sophisticated,molecular mechanism-based paradigms in diabetes classification.关键词
糖尿病分型/病因分子机制/早期诊断/个性化治疗Key words
diabetes classification/etiological molecular mechanism/early diagnosis/precision medicine分类
医药卫生引用本文复制引用
杨舒婷,罗说明,周智广..糖尿病分型新视野——基于临床表现向基于病因分子机制转变[J].实用医学杂志,2024,40(16):2199-2205,7.基金项目
湖南省自然科学基金重大项目(揭榜制)(编号:2021JC0003) （揭榜制）
湖南省临床医疗技术创新引导项目(编号:2021SK53508) （编号:2021SK53508）
湖南省卫生健康高层次人才重大科研专项(编号:R202344,R2023050) （编号:R202344,R2023050）
