2型糖尿病的缓解:百家争鸣与脚踏实地OA北大核心CSTPCD
Remission of type 2 diabetes:Contending perspectives and practical approaches
在2型糖尿病早期,诱导高血糖的缓解已成为糖尿病管理领域的全球性热点.近年来,中外学者建立了包括短期胰岛素强化治疗、生活方式干预、代谢性手术等多个缓解干预手段,提出了β细胞去分化、肝-胰腺双循环等理论,使本领域的临床和研究信息加速增长.本文对糖尿病缓解领域的临床证据、基础机制、适用人群、实施要点等方面进行了综述,以期加深临床工作者对糖尿病缓解的认识,为更好地进行相关领域的实践和探索奠定基础.
In the early stages of type 2 diabetes,inducing remission of hyperglycemia has become a global hotspot in the field of diabetes management.In recent years,scholars from both domestic and international commu-nities have established several remission intervention methods,including short-term intensive insulin therapy,life-style intervention,and metabolic surgery.They have also proposed theories such as beta-cell dedifferentiation and liver-pancreas"twin cycle"hypothesis,which have accelerated the growth of clinical and research information in this field.This review summarizes the clinical evidence,basic mechanisms,applicable populations,and exacutive principle points in the field of diabetes remission,with the aim of deepening the understanding of clinical practitio-ners about diabetes remission and laying the foundation for better practice and research in related fields.
刘烈华;李延兵
中山大学附属第一医院(广州 510080)
临床医学
2型糖尿病缓解β细胞功能
type 2 diabetes mellitusremissionabetes mellitus
《实用医学杂志》 2024 (016)
2206-2210 / 5
国家重点研发计划项目(编号:2018YFC1314100,2022YFC2505202);广东省自然科学基金(编号:2023A1515012321);广东省重点领域研发计划项目(编号:2019B020230001);广州市科技计划项目(编号:202002020053);广州地区临床特色项目(编号:2023P-TS06)
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