同位素2024，Vol.37Issue(4)：399-405,7.DOI:10.7538/tws.2024.youxian.032
锝[99mTc]放射性药品注射用配套药盒中Sn(Ⅱ)含量测定方法概述
Overview of the Methods for Determination of Sn(Ⅱ)in Technetium[99mTc]Radiopharmaceutical Injection Kits
杨佳宁 1崔晓艳 1王玉玺 1王勇 1李岩 1杨柳1
作者信息
- 1. 原子高科股份有限公司,北京 102413
- 折叠
摘要
Abstract
The content of stannous chloride is one of the key indicators for the quality control of Technetium[99mTc]radiopharmaceutical injection Kits,which directly affects the clinical use of Technetium[99mTc]radiopharmaceuticals.Consequently,it is crucial to choose the appropriate analytical method for its accurate determination.By comparing the quality standards of radiopharmaceuticals included in the 2020 edition of the Chinese Pharmacopoeia and other related literature,the characteristics,determination principles and applications of commonly used methods for the determination of stannous chloride,including potentiometric analysis,spectrophotometry and high-performance liquid chromatography,were analyzed and summarized.This work provided technical reference for the establishment of a more scientific and rational quality standard for Technetium[99mTc]radiopharmaceutical injection kits.关键词
锝[99mTc]放射性药品注射用配套药盒/氯化亚锡含量测定/电位分析法/分光光度法/高效液相色谱法Key words
Technetium[99mTc]radiopharmaceutical injection kits/stannous chloride determination/potentiometric analysis/spectrophotometry/HPLC分类
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杨佳宁,崔晓艳,王玉玺,王勇,李岩,杨柳..锝[99mTc]放射性药品注射用配套药盒中Sn(Ⅱ)含量测定方法概述[J].同位素,2024,37(4):399-405,7.
