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基于倾向性评分匹配法比较术前贫血对胃癌术后近期疗效及远期预后的影响

吴丹缘 颜优贞 林鸿珍

现代医药卫生2024,Vol.40Issue(16):2713-2718,6.
现代医药卫生2024,Vol.40Issue(16):2713-2718,6.DOI:10.3969/j.issn.1009-5519.2024.16.003

基于倾向性评分匹配法比较术前贫血对胃癌术后近期疗效及远期预后的影响

Comparison of the effect of preoperative anemia on the short-term efficacy and long-term prognosis of gastric cancer surgery based on propensity score matching method

吴丹缘 1颜优贞 1林鸿珍1

作者信息

  • 1. 福建医科大学肿瘤临床医学院/福建省肿瘤医院胃肠肿瘤外科,福建 福州 350014
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摘要

Abstract

Objective To investigate the comparison of the effect of preoperative anemia on short-term therapeutic outcomes and long-term prognosis after gastrectomy for gastric cancer based on propensity score matching method.Methods A total of 1274 patients with gastric cancer treated at our hospital from February 2011 to March 2018 were selected.Based on the presence or absence of anemia,they were divided into the ane-mia group(372 cases)and the non-anemia group(902 cases).Propensity score matching was performed in a 1∶1 ratio,successfully matching 328 pairs of patients.The postoperative recovery and prognosis were com-pared between the two groups.Results The incidence of preoperative anemia among the 1274 patients was 29.2%(372/1274).Age,body mass index(BMI),diabetes,preoperative anemia,extent of resection,and op-erative time were independent risk factors for postoperative complications(P<0.05).Before matching,signif-icant differences were observed between the two groups in terms of age,BMI,diabetes,tumor size,surgical ap-proach,and pathological stage(P<0.05).After matching,no significant differences were found in general characteristics between the two groups(P>0.05).Compared to the non-anemia group,the anemia group had higher rates of postoperative complications and longer hospital stays,both with statistical significance(P<0.05).The 5-year survival rate of the anemia group was significantly lower than that of the non-anemia group(P<0.05).Conclusion Preoperative anemia increases the incidence of postoperative complications,prolongs postoperative recovery,and adversely affects prognosis.

关键词

胃癌/术前贫血/并发症/倾向性评分匹配法

Key words

Gastric cancer/Preoperative anemia/Complication/Propensity score matching

分类

医药卫生

引用本文复制引用

吴丹缘,颜优贞,林鸿珍..基于倾向性评分匹配法比较术前贫血对胃癌术后近期疗效及远期预后的影响[J].现代医药卫生,2024,40(16):2713-2718,6.

现代医药卫生

1009-5519

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