现代医药卫生2024,Vol.40Issue(16):2723-2726,2731,5.DOI:10.3969/j.issn.1009-5519.2024.16.005
伴多种并发症的Ⅰ型自身免疫性多内分泌腺病综合征1例及文献复习
A case of type Ⅰ autoimmune polyendocrinopathy syndrome with multiple complications and review of the literature
摘要
Abstract
This paper reports the clinical data of a 53-year-old middle-aged female patient who was ad-mitted to the hospital with dizziness,fatigue,nausea,vomiting for 3 days and diarrhea.The Clinical examina-tion showed that the patient had a variety of autoimmune and non-immune manifestations,accompanied by a variety of complications.The main disease are oral candida infection,type Ⅰ diabetes,Hashimoto thyroiditis hypothyroidism,and moderate to severe non-segmental vitiligo.At the same time,it was found that the patient had metabolic syndrome,including high-density lipoprotein deficiency,hypertension grade 1(very high risk group)and diabetic ketoacidosis,diabetic peripheral neuropathy,diabetic nephropathy(stage G2A1),and dia-betic peripheral vasculopathy.In addition,the patient had multiple complications such as hypoproteinemia,subclavian artery plaque,common carotid artery plaque,depressive status,and osteoporosis,and was clinically diagnosed as type Ⅰ autoimmune polyendocrine syndrome.The patient recovered well after comprehensive treatment during hospitalization and continued to take medication after discharge.关键词
自身免疫性多内分泌综合征Ⅰ型/口腔念珠菌感染/甲状腺功能减退/Ⅰ型糖尿病/白癜风/病例报告/文献复习Key words
Type Ⅰ autoimmune polyendocrinopathy syndrome/Oral candida infection/Hypothy-roidism/Type Ⅰ diabetes/Vitiligo/Case report/Literature review分类
医药卫生引用本文复制引用
和彩玲,赵蓉,尹虹,王百灵..伴多种并发症的Ⅰ型自身免疫性多内分泌腺病综合征1例及文献复习[J].现代医药卫生,2024,40(16):2723-2726,2731,5.基金项目
2021年兰州市卫生健康科技发展项目(2021014) (2021014)
2020年兰州市科技发展指导性计划项目(2020-zd-115). (2020-zd-115)