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20 Hz重复经颅磁刺激联合文拉法辛治疗成人广泛性焦虑障碍的效果研究

楚孔渠 甘景梨 段惠峰 梁学军

现代医药卫生2024,Vol.40Issue(16):2727-2731,5.
现代医药卫生2024,Vol.40Issue(16):2727-2731,5.DOI:10.3969/j.issn.1009-5519.2024.16.006

20 Hz重复经颅磁刺激联合文拉法辛治疗成人广泛性焦虑障碍的效果研究

Study on the effects of 20 Hz repetitive transcranial magnetic stimulation combined with venlafaxine in the treatment of adult generalized anxiety disorders

楚孔渠 1甘景梨 1段惠峰 1梁学军1

作者信息

  • 1. 中国人民解放军联勤保障部队第九八八医院全军精神疾病防治研究所,河南 焦作 454003
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摘要

Abstract

Objective To observe the effects of 20 Hz repetitive transcranial magnetic stimulation(rT-MS)combined with venlafaxine in the treatment of adult generalized anxiety disorder(GAD)and its impact on cognitive function and negative emotions.Methods A total of 75 adult patients with GAD admitted to the hospital from March 2021 to April 2023 were randomly divided into two groups using the random number ta-ble method.The control group(37 cases)received venlafaxine treatment,while the study group(38 cases)re-ceived rTMS on the basis of venlafaxine.The clinical efficacy of the two groups was compared.Results The total effective rate,eye movement measurement,Montreal Cognitive Assessment Scale(MoCA)scores in the study group were higher than those in the control group,and the event-related potential latency,as well as the scores of GAD-7 scale,Hamilton Anxiety Scale and Hamilton Depression Scale were significantly lower than those of the control group,with statistical significance(P<0.05).Conclusion The 20 Hz repetitive transcra-nial magnetic stimulation combined with venlafaxine therapy can improve the clinical efficacy,cognitive func-tion,and alleviate negative emotions in adult patients with GAD,with high therapeutic practicality.

关键词

重复经颅磁刺激/文拉法辛/成年人/广泛性焦虑障碍/认知功能/负性情绪

Key words

Repetitive transcranial magnetic stimulation/Venlafaxine/Adult/Generalized anxie-ty disorder/Cognitive function/Negative emotions

分类

医药卫生

引用本文复制引用

楚孔渠,甘景梨,段惠峰,梁学军..20 Hz重复经颅磁刺激联合文拉法辛治疗成人广泛性焦虑障碍的效果研究[J].现代医药卫生,2024,40(16):2727-2731,5.

基金项目

河南省医学科技攻关计划项目(LHGJ20200791). (LHGJ20200791)

现代医药卫生

1009-5519

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