百乐眠胶囊联合黛力新对睡眠障碍患者睡眠结构相关指标、睡眠质量及神经递质水平的影响OA

Objective To investigate the effect of Bailemien capsule combined with Delisin on sleep structure related indexes,sleep quality and neurotransmitter levels in patients with sleep disorders(SD).Methods A total of 98 SD patients treated in our hospital from January 2022 to September 2023 were divided into the control group and the observation group with 49 cases in each group by random number method.The control group was treated with Delisin,and the observation group was treated with Bailimian capsule on the basis of Delisin treatment.The sleep structure related indexes[including sleep onset latency(SOL),total sleep time(TST)and sleep efficiency(SE)],sleep quality[Pittsburgh Sleep Quality Index(PSQI)score],and neurotransmitter levels[including norepinephrine(NE),5-hydroxytryptamine(5-HT)and gamma-aminobu-tyric acid(GABA)]were compared between the two groups.Results After treatment,the SOL,PSQI scores and NE levels of the two groups were significantly decreased,TST and SE were significantly increased,5-HT and GABA levels were significantly increased,and the SOL,TST,SE and PSQI scores,as well as NE,5-HT and GA-BA levels of the observation group were superior to the control group after treatment.The differences were statistically significant(P<0.05).Conclusion Bailemien capsule combined with Delisin can regulate the level of neurotransmitter in SD patients,improve the related indexes of sleep structure and improve sleep quality.