中国动物检疫2024，Vol.41Issue(8)：61-68,8.DOI:10.3969/j.issn.1005-944X.2024.08.013
我国牛源金黄色葡萄球菌耐药情况及防控研究进展
Drug Resistance of Bovine Staphylococcus aureus and Research Progress on Its Control Strategies in China
摘要
Abstract
Staphylococcus aureus(S.aureus)is one of the common causes of cow mastitis,which could be effectively prevented and treated only by antibiotics.It,however,is resistant to a variety of antibiotics due to prolonged use of antibiotics,and makes animals become the reservoir of drug-resistant genes,posing a threat to food safety and human health.It is found that,based on domestic relevant researches on bovine S.aureus,the drug resistance rate of bovine S.aureus has been increasing in China with worsening multi-drug resistance,especially in the northern high-latitude regions;rich molecular epidemiological characteristics are found,dominated by ST9,ST97 and ST398 types that are widely distributed,MRSA SCCmec Ⅻ,SCCmec Ⅲ and SCCmec Ⅳ tend to spread diffusively;antibiotic substitutions with a better prospect including Chinese medicinal preparation,phage,probiotics and antimicrobial peptide are under development to solve the drug resistance of S.aureus.Here,the drug resistance of bovine S.aureus and the research progress of its prevention and control technologies in China were reviewed,supporting future prevention and control of such drug resistance.关键词
金黄色葡萄球菌/抗微生物药物耐药性/耐药防控Key words
S.aureus/anti-microbial resistance/prevention and control of drug resistance分类
畜牧业引用本文复制引用
胡方圆,赵建梅,刘俊辉,曲志娜,王君玮,王琳,刘耀蓬,宋时萍,郭皖露,刘娜,高玉斌,王娟,黄秀梅..我国牛源金黄色葡萄球菌耐药情况及防控研究进展[J].中国动物检疫,2024,41(8):61-68,8.基金项目
国家重点研发计划项目(2022YFC2303900) （2022YFC2303900）
中国动物卫生与流行病学中心创新基金项目(DW2021018) （DW2021018）
