中国感染控制杂志2024，Vol.23Issue(8)：942-953,12.DOI:10.12138/j.issn.1671-9638.20245425
湖南省细菌耐药监测网2012-2021年ICU分离细菌耐药性监测报告
Antimicrobial resistance of bacteria from intensive care units:surveillance report from Hunan Province Antimicrobial Resistance Surveillance Sys-tem,2012-2021
摘要
Abstract
Objective To investigate the distribution and antimicrobial susceptibility of clinically isolated bacteria from intensive care units(ICUs)in hospitals of Hunan Province Antimicrobial Resistance Surveillance System from 2012 to 2021.Methods According to China Antimicrobial Resistance Surveillance System,data of clinically isolated bacterial strains and antimicrobial susceptibility testing results of bacteria from ICUs reported by all member units of Hunan Province Antimicrobial Resistance Surveillance System were analyzed with WHONET 2022 software.Results From 2012 to 2021,the total number of bacteria isolated from ICUs of member units of the Hunan Province Antimi-crobial Resistance Surveillance System was 5 777-22 369,with Gram-negative bacteria accounting for 76.1％-78.0％annually.Staphylococcus aureus ranked first among isolated Gram-positive bacteria each year.The top 5 bacteria among Gram-negative bacteria were Acinetobacter baumannii,Klebsiella pneumoniae,Escherichia coli,Pseudo-monas aeruginosa,and Stenotrophomonas maltophilia.Detection rate of methicillin-resistant Staphylococcus aureus showed a downward trend year by year.No Staphylococcus spp.were found to be resistant to vancomycin,teico-planin and linezolid.Detection rates of vancomycin-resistant Enterococcus faecalis and vancomycin-resistant Entero-coccus faecium were 0.6-1.1％and 0.6％-2.2％,respectively.Resistance rates of Escherichia coli and Kleb-siella pneumoniae to imipenem were 3.1％-5.7％and 7.7％-20.9％,respectively.Resistance rates of Pseudo-monasaeruginosa and Acinetobacter baumannii to imipenem were 24.6％-40.1％and 76.1％-80.9％,respective-ly.Detection rates of carbapenem-resistant Pseudomonas aeruginosa declined year by year.Acinetobacter baumannii maintained high susceptibility to polymyxin B,with resistance rate＜10％.Conclusion Antimicrobial resistance of bacteria from ICUs is serious.Carbapenem-resistant Enterobacteriales has an upward trend after 2019.It is nece-ssary to strengthen the surveillance of bacterial resistance and carry out multidisciplinary collaboration.关键词
病原菌/耐药性/重症监护病房/耐碳青霉烯类革兰阴性菌/湖南省细菌耐药监测网Key words
pathogen/antimicrobial resistance/intensive care unit/carbapenem-resistant Gram-negative bacteria/Hunan Province Antimicrobial Resistance Surveillance System分类
医药卫生引用本文复制引用
陈丽华,袁红霞,郑铭,任南,黄勋,吴安华,周建党,付陈超,李晨,李艳明,刘君,宁兴旺,石国民,邬靖敏,杨怀德..湖南省细菌耐药监测网2012-2021年ICU分离细菌耐药性监测报告[J].中国感染控制杂志,2024,23(8):942-953,12.基金项目
湖南省自然科学基金项目(2021JJ30996) （2021JJ30996）
