中国感染控制杂志2024，Vol.23Issue(8)：1031-1036,6.DOI:10.12138/j.issn.1671-9638.20245131
一起疑似新生儿耐碳青霉烯类肺炎克雷伯菌血流感染聚集性事件的调查与处置
Investigation and disposal of a cluster of suspected neonatal bloodstream infection with carbapenem-resistant Klebsiella pneumoniae
摘要
Abstract
Objective To investigate the causes of a cluster of suspected neonatal carbapenem-resistant Klebsiella pneumoniae(CRKP)bloodstream infection(BSI)in the neonatal department of a hospital,and provide references for the effective control of the occurrence of healthcare-associated infection(HAI).Methods Epidemiological in-vestigation on 3 neonates with CRKP BSI in the neonatal department from January 31 to February 6,2023 was per-formed.Specimens from environmental object surfaces were taken for environmental hygiene monitoring,and effec-tive control measures were taken according to the risk factors.Results From January 31 to February 6,2023,a to-tal of 60 neonates were admitted in the neonatal department,including 16 with peripherally inserted central venous catheter(PICC).Three neonates had CRKP BSI,with a incidence of 5.00％.There were 33 hospitalized neonates on the day(February 7)when the cluster of HAI was reported,with a prevalence rate of 9.09％(3/33).CRKP BSI rate in the neonatal department of this hospital from January 31 to February 6,2023 was higher than that in 2022(P＜0.001).The incubators of the 3 neonates with CRKP BSI were in the same ward and adjacent to each other.The first neonate with CRKP BSI(who developed BSI on January 31)underwent PICC maintenance on Feb-ruary 4,and the other 2 neonates with PICC maintenance immediately following the first one also developed CRKP BSI.CRKP were isolated from blood culture of all 3 neonates,and antimicrobial susceptibility testing results were consistent.Conclusion The occurrence of the cluster event of neonatal CRKP BSI may be related to the failure of strict implementation of aseptic procedures during PICC maintenance and cross contamination among items.关键词
新生儿/耐碳青霉烯类肺炎克雷伯菌/血流感染/聚集性事件/PICC/CRBSIKey words
neonate/carbapenem-resistant Klebsiella pneumoniae/bloodstream infection/cluster event/PICC/CRBSI分类
医药卫生引用本文复制引用
李育林,徐艳,牟霞,陈文婷,李雪云,聂婵,韩松涛,陈黎媛,唐兰,王振宇,李亚慧..一起疑似新生儿耐碳青霉烯类肺炎克雷伯菌血流感染聚集性事件的调查与处置[J].中国感染控制杂志,2024,23(8):1031-1036,6.基金项目
贵阳市科技计划基金项目(筑科合同[2022]-4-1-5号) （筑科合同[2022]-4-1-5号）
