3种不同内窥镜联合诊断对提高早期食管癌诊断率的应用价值评估OACSTPCD

Objective:To explore and analyze the application value of the combined diagnosis of three kinds of different endoscopies in improving the diagnosis rate of early esophageal cancer.Methods:The clinical data of 110 patients with early esophageal cancer and(or)precancerous lesions,who admitted to the First Affiliated Hospital of Xinjiang Medical University from March 2020 to February 2022,were retrospectively analyzed.According to the diagnostic results of pathology,they were divided into esophageal cancer group(65 cases)and inflammation group(45 cases).Both groups of patients were diagnosed and examined by ultrasound endoscopy,iodine staining endoscopy and magnifying endoscopy with narrow band imaging(ME-NBI).Univariate analysis was used to explore the high-risk factors affecting the diagnostic value of early esophageal cancer.The logistic multivariate regression analysis was used to explore the diagnostic values of them on early esophageal cancer.The efficacies of diagnostic methods of different endoscopies for early esophageal cancer were compared.The area under curve(AUC)values of receiver operating characteristic(ROC)curves among different stages(the first,second,third and fourth stage)of chromosome were compared.Results:There were no significant differences in age,median age,lesion location,circumferential area and lesion status under ultrasound endoscope between the inflammation group and the esophageal cancer group(P>0.05).There were significant differences in the manifestations under iodine staining endoscope,ME-NBI intraepithelial papillary capillary loop(IPCL)typing and straw mat sign between the inflammation group and the esophageal cancer group(x2=5.995,20.168,5.960,P<0.05),respectively.The depth of lesion infiltration,the changes of iodine staining and straw mat sign of ultrasound gastroscopy,iodine staining endoscopy and ME-NBI were included in the logistic regression analysis equation.The results showed that the AUC value of the fourth stage was significantly higher than that of the first,second and third stages,and the AUC value of the third stage was significantly higher than that of the first and second stages,and the ACU value of the second stage was significantly higher than that of the first stage,respectively,and the AUC was 9.663(95%CI:0.935-9.551,P<0.05).In diagnosing early esophageal cancer,the sensitivity and specificity of the combined endoscopy were significantly higher than those of ultrasound endoscopy,iodine staining endoscopy and ME-NBI alone,and the differences were statistically significant(x2=5.409,27.948,x2=12.819,19.786,x2=9.148,15.294,P<0.05).Conclusion:The combined diagnosis of different types of endoscopes for early esophageal cancer is significantly better than that of a single endoscopy method,and the combined diagnosis has higher diagnostic accuracy for early esophageal cancer.