中国药业2024，Vol.33Issue(16)：48-51,4.DOI:10.3969/j.issn.1006-4931.2024.16.011
AHP-CRITIC法结合正交试验法优选如意凝胶贴膏提取工艺
Optimization of Extraction Process of Ruyi Gel Plaster by AHP-CRITIC Combined with Orthogonal Test
摘要
Abstract
Objective To optimize the extraction process of Ruyi Gel Plaster.Methods The geniposide content,baicalin content and dry extract yield were taken as the evaluation indicators,the analytic hierarchy process(AHP)-CRITIC method was used to determine their weight coefficients.The orthogonal test was used to optimize the extraction process of Ruyi Gel Plaster with the water addition amount,soaking time and extraction time as the investigation factors.Then the verification test was carried out.Results The optimal process was as follows:adding 12 times the amount of water for the first time,extracting for 2.0 h;adding 10 times the amount of water for the second time,extracting for 1.5 h.Based on the optimal extraction process,the dry extract yield,geniposide content and baicalin content of the samples were in the range of 24.11%-24.23%,2.20-2.25 mg/g and 12.10-12.15 mg/g,respectively.Conclusion The optimal extraction process is scientific and reasonable,which can provide a basis for the follow-up research and development of Ruyi Gel Plaster.关键词
如意凝胶贴膏/提取工艺/层次分析法/客观赋权法/干膏得率Key words
Ruyi Gel Plaster/extraction process/analytic hierarchy process/objective weighting method/dry extract yield分类
医药卫生引用本文复制引用
刘秋叶,左亚杰,何雄,郑沛,文玲,杨俊,王潇,文敏..AHP-CRITIC法结合正交试验法优选如意凝胶贴膏提取工艺[J].中国药业,2024,33(16):48-51,4.基金项目
国家中医药管理局中药炮制技术传承基地建设项目[国中医药科技中药便函[2022]59号] （）
湖南省自然科学基金[2021JJ80066,2023JJ60112] （）
湖南中医药大学校级科研基金项目[2019XJJJ053]. （）
