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基于倾向性评分匹配法的脑膜瘤切除术后感染危险因素分析

黄磊 宋璐 张琳琳 吴慧 王阿明 尹存林 胡晔

中国药业2024,Vol.33Issue(16):103-106,4.
中国药业2024,Vol.33Issue(16):103-106,4.DOI:10.3969/j.issn.1006-4931.2024.16.024

基于倾向性评分匹配法的脑膜瘤切除术后感染危险因素分析

Risk Factors for Infection After Meningioma Resection Based on Propensity Score Matching

黄磊 1宋璐 1张琳琳 1吴慧 1王阿明 1尹存林 1胡晔1

作者信息

  • 1. 南京大学医学院附属盐城第一医院,江苏 盐城 224005
  • 折叠

摘要

Abstract

Objective To investigate the risk factors for infection after meningioma resection.Methods A total of 288 patients who underwent meningioma resection in the hospital from January 2020 to December 2021 were selected and retrospectively analyzed.They were divided into the infected group(91 cases)and the uninfected group(197 cases)based on whether postoperative infection occurred.The two groups were matched at 1∶1 by the propensity score matching(PSM)method.The independent risk factors for infection after meningioma resection were evaluated by the Logistic regression model.Results A total of 61 pairs of patients were successfully matched.The Logistic regression analysis showed that the surgical duration>4 h[OR=2.481,95%CI(1.126,5.466),P=0.024],irrational selection of preventive medication[OR=6.220,95%CI(1.231,31.423),P=0.027]and indwelling drainage tube[OR=2.634,95%CI(1.196,5.802),P=0.016]were the independent risk factors for infection after meningioma resection.Conclusion Clinical pharmacists should strengthen the education on the rational use of preventive medication for physicians,and provide individualized pharmaceutical care and medication monitoring for patients with surgical duration>4 h and indwelling drainage tube.

关键词

脑膜瘤切除手术/术后感染/危险因素/倾向性评分匹配法/合理用药

Key words

meningioma resection/postoperative infection/risk factor/propensity score matching/rational drug use

分类

医药卫生

引用本文复制引用

黄磊,宋璐,张琳琳,吴慧,王阿明,尹存林,胡晔..基于倾向性评分匹配法的脑膜瘤切除术后感染危险因素分析[J].中国药业,2024,33(16):103-106,4.

基金项目

江苏省研究型医院学会精益化用药-石药专项科研基金[JY202242] ()

江苏省老年医学学会临床药学专项基金[JGS2023ZDYX001]. ()

中国药业

OACSTPCD

1006-4931

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