加味苍术泄浊饮对高尿酸血症患者尿酸及血脂水平的影响OACSTPCD

Objective To analyze the effects of modified Cangzhu Xiezhuo Drink on the uric acid(UA)and blood lipid levels in patients with hyperuricemia.Methods A total of 100 patients with hyperuricemia admitted to the hospital from March 2021 to December 2022 were selected and randomly divided into the observation group and the control group,with 50 cases in each group.The patients in the two groups were given routine lifestyle interventions and oral Allopurinol Sustained-Release Capsules,on this basis,the patients in the observation group were given modified Cangzhu Xiezhuo Drink.Both groups were treated for four weeks.Results The total effective rate in the observation group was 94.00%,which was significantly higher than 78.00%in the control group(P<0.05).Compared with those in the control group,the scores of traditional Chinese medicine(TCM)syndromes(joint pain,joint swelling,restricted activities,body coldness,body heat)after treatment in the observation group significantly decreased,the UA,potassium ions and sodium ions levels significantly decreased,the total cholesterol(TC)and triglyceride(TG)levels significantly decreased(P<0.05).The incidence of adverse reactions in the observation group was similar to that in the control group(12.00%vs.6.00%,P>0.05).Conclusion Compared with the use of allopurinol alone,the modified Cangzhu Xiezhuo Drink combined with allopurinol is more effective in improving the relevant clinical symptoms of patients with hyperuricemia,regulating the UA and electrolyte levels,and decreasing the blood lipid levels.