中国药业2024，Vol.33Issue(16)：120-124,5.DOI:10.3969/j.issn.1006-4931.2024.16.029
基于属性层次模型加权逼近理想解排序法的阿哌沙班药物利用评价
Drug Use Evaluation of Apixaban Based on Attribute Hierarchical Model Weighted Technique for Order Preference by Similarity to Ideal Solution
摘要
Abstract
Objective To promote the rational use of apixaban in clinical practice.Methods According to the drug instruction,the drug use evaluation(DUE)criteria for apixaban was formulated based on relevant guidelines and literature.The indicators of the DUE criteria for apixaban were weighted by the attribute hierarchy model(AHM),the rationality of medical records of patients using apixaban in the hospital from August 2021 to July 2022 was evaluated by the technique for order preference by similarity to ideal solution(TOPSIS)method.Results A total of three primary indicators and 12 secondary indicators were formed.A total of 102 medical records(involving 102 patients)were included,including 52 males and 50 females,with non-valvular atrial fibrillation(52 cases)and prevention of venous thrombosis(30 cases)as the main indications for medication.The secondary indicators with high relative weight coefficients were the indications(0.108),drug conversion(0.107)and contraindications(0.089);the top three secondary indicators with high irrational rate were usage and dosage(61.76%),indications(44.12%)and combined medication(38.24%).The drug use in 15 cases(14.71%),61 cases(59.80%),26 cases(25.49%)were evaluated as rational[relative closeness to optimal plan(Ci)≥0.8],generally rational(0.6≤Ci<0.8),irrational(Ci<0.6)respectively.Conclusion It is feasible to evaluate the rationality of apixaban use based on AHM weighted TOPSIS method.The use of apixaban in this hospital is generally rational,but there are still problems in indications,combined medication,usage and dosage.Clinicians and pharmacists should strengthen the intervention to promote the rational use of apixaban.关键词
属性层次模型/逼近理想解排序法/阿哌沙班/药物利用评价/合理用药Key words
attribute hierarchy model/technique for order preference by similarity to ideal solution/apixaban/drug use evaluation/rational drug use分类
医药卫生引用本文复制引用
曹迪,程军,司福国,汪龙,陈伟强..基于属性层次模型加权逼近理想解排序法的阿哌沙班药物利用评价[J].中国药业,2024,33(16):120-124,5.基金项目
安徽省蚌埠市科技创新指导类项目[20200322]. （）
