中国医药科学2024，Vol.14Issue(14)：17-20,4.DOI:10.20116/j.issn2095-0616.2024.14.04
线粒体自噬在急性胰腺炎中的研究进展
Research progress of mitochondrial autophagy in acute pancreatitis
摘要
Abstract
As one of the common acute abdominal diseases in clinic,acute pancreatitis(AP)has a complicated pathogenesis,accompanied by mitochondrial damage and dysfunction of acinar cells,lymphocytes and other cells.Mitochondrial autophagy,an important way to regulate cell homeostasis,can target and remove damaged and dysfunctional mitochondria in cells.It is found that mitochondrial autophagy participates in the occurrence and development of AP.Mitochondrial quality control through mitochondrial autophagy can alleviate AP and can be used as a key target for AP treatment.In this paper,the signal pathways related to mitochondrial autophagy and the research progress of mitochondrial autophagy in AP are summarized,so as to provide theoretical reference for mitochondrial autophagy as the target for AP treatment.关键词
急性胰腺炎/线粒体自噬/线粒体功能障碍/信号通路Key words
Acute pancreatitis/Mitochondrial autophagy/Mitochondrial dysfunction/Signal pathway分类
医药卫生引用本文复制引用
岑兰英,黄秀权,王语阳,苏拾香,覃宗帅,甘慧芳,覃月秋..线粒体自噬在急性胰腺炎中的研究进展[J].中国医药科学,2024,14(14):17-20,4.基金项目
国家自然科学基金(82260134) （82260134）
广西自然科学基金项目(2023GXNSFAA026118) （2023GXNSFAA026118）
右江民族医学院附属医院高层次人才科研项目(R202011702) （R202011702）
2023年右江民族医学院研究生创新计划项目(YZCXJH2023002). （YZCXJH2023002）
