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艾司氯胺酮抗产后抑郁的临床应用

欧阳文志 田志海

中国医药科学2024,Vol.14Issue(14):29-32,4.
中国医药科学2024,Vol.14Issue(14):29-32,4.DOI:10.20116/j.issn2095-0616.2024.14.07

艾司氯胺酮抗产后抑郁的临床应用

Clinical application of esketamine in the treatment of postpartum depression

欧阳文志 1田志海2

作者信息

  • 1. 吉首大学医学院,湖南吉首 416000
  • 2. 湖南省湘西自治州人民医院麻醉科,湖南吉首 416000
  • 折叠

摘要

Abstract

Depression after cesarean section seriously harms the physical and mental health of mother and baby,affects family harmony,and aggravates social and economic burden.The prevention and treatment of maternal depression is of self-evident importance.Ketamine,as an antidepressant,has attracted much attention in the treatment of mental illness.As the S-enantiomer of ketamine,esketamine,a new anesthetic,has stronger affinity with N-methyl-D-aspartic acid receptor and fewer adverse reactions.Previous studies showed that the antidepressant effect on treatment-refractory depression and major depressive disorder of esketamine is not inferior to that of ketamine,indicating esketamine has a good application prospect in the prevention and treatment of depression after cesarean section.This paper mainly expounds the clinical application of esketamine in the treatment of postpartum depression.

关键词

艾司氯胺酮/剖宫产/麻醉/抑郁症

Key words

Esketamine/Cesarean section/Anesthesia/Depression

分类

医药卫生

引用本文复制引用

欧阳文志,田志海..艾司氯胺酮抗产后抑郁的临床应用[J].中国医药科学,2024,14(14):29-32,4.

基金项目

湖南省医学会医学科研基金-围术期管理及抗抑郁新型药物临床研究科研项目(HMA202101025). (HMA202101025)

中国医药科学

2095-0616

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