中国医药科学2024，Vol.14Issue(14)：55-58,101,5.DOI:10.20116/j.issn2095-0616.2024.14.13
阿司匹林与蛛网膜下腔出血相关性的meta分析
Meta-analysis of correlation between aspirin and subarachnoid hemorrhage
摘要
Abstract
Objective To evaluate the correlation between aspirin and subarachnoid hemorrhage(SAH).Methods The domestic and foreign databases,such as PubMed and CNKI,were retrieved by computer,and the retrieval time was from the establishment of the database to April 2023.The researchers comprehensively evaluated the results of the included documents.Results Finally,12 articles were included.Meta-analysis showed that aspirin could significantly reduce the risk of SAH(OR=0.61,95％CI:0.42-0.88,P=0.007).Subgroup analysis showed that in the general population,aspirin had no statistically significant impact on SAH(OR=1.00,95％CI:0.72-1.40,P=0.98).However,in patients with intracranial aneurysms,aspirin had a protective effect(OR=0.32,95％CI:0.20-0.53,P＜0.000 01).Conclusion Aspirin can reduce the risk of SAH in patients with intracranial aneurysms,but it has no protective effect on the general population.关键词
阿司匹林/蛛网膜下腔出血/颅内动脉瘤/meta分析Key words
Aspirin/Subarachnoid hemorrhage/Intracranial aneurysm/Meta-analysis分类
医药卫生引用本文复制引用
柯义君,王威,陈燕,黄灿,金涌,齐腊梅..阿司匹林与蛛网膜下腔出血相关性的meta分析[J].中国医药科学,2024,14(14):55-58,101,5.基金项目
安徽省重点研究与开发计划项目(2022e07020040) （2022e07020040）
安徽省安庆市医疗卫生类自筹经费科技计划项目(2022Z2001). （2022Z2001）
