中国医药科学2024，Vol.14Issue(14)：163-166,4.DOI:10.20116/j.issn2095-0616.2024.14.39
探讨补充维生素D对妊娠期糖尿病合并亚临床甲状腺功能减退患者的临床治疗效果
Investigation on the clinical therapeutic efficacy of vitamin D supplementation on gestational diabetes mellitus complicated with subclinical hypothyroidism
赵慧 1庞丽 1王令令 2高爱滨1
作者信息
- 1. 山东省滨州市中心医院内分泌科,山东滨州 251700
- 2. 山东省滨州市人民医院全科医学科,山东滨州 256600
- 折叠
摘要
Abstract
Objective To investigate the clinical effects of vitamin D treatment in patients with gestational diabetes mellitus(GDM)complicated by subclinical hypothyroidism.Methods A total of 90 patients with GDM complicated by subclinical hypothyroidism admitted to Binzhou Central Hospital from March 2021 to February 2023 were randomly divided into two groups,with 45 patients in each group.The control group received basic treatment,while the observation group received vitamin D treatment in addition to the basic treatment.Both groups were treated continuously for one month.Blood glucose and thyroid function indicators were compared between the two groups,and the incidence of adverse pregnancy outcomes was statistically analyzed.Results After treatment,the observation group had significantly lower levels of fasting blood glucose,2-hour postprandial blood glucose,glycated hemoglobin,and incidence of adverse pregnancy outcomes compared to the control group.The observation group also had significantly lower levels of thyroid-stimulating hormone and higher levels of thyroxine,25-hydroxyvitamin D2,and serum calcium ions compared to the control group,with statistically significant differences(P＜0.05).Conclusion Vitamin D supplementation in patients with gestational diabetes mellitus complicated by subclinical hypothyroidism can help regulate blood glucose and thyroid function indicators,reduce the risk of adverse pregnancy outcomes,and improve prognosis.关键词
维生素D/妊娠期糖尿病/甲状腺功能减退/妊娠结局Key words
Vitamin D/Gestational diabetes mellitus/Hypothyroidism/Pregnancy outcome分类
医药卫生引用本文复制引用
赵慧,庞丽,王令令,高爱滨..探讨补充维生素D对妊娠期糖尿病合并亚临床甲状腺功能减退患者的临床治疗效果[J].中国医药科学,2024,14(14):163-166,4.
