肿瘤防治研究2024，Vol.51Issue(8)：625-629,5.DOI:10.3971/j.issn.1000-8578.2024.24.0044
骨肉瘤相关基因多态性的研究进展
Research Progress on Gene Polymorphisms Related to Osteosarcoma
摘要
Abstract
Osteosarcoma,which primarily affects children and adolescents,is a highly malignant bone tumor with high rates of disability and mortality.Therefore,the exploration of biological markers related to its occurrence,development,and prognosis is crucial.Genome-wide association studies have revealed the vital role of genetic polymorphisms in the pathogenesis of osteosarcoma.This study aims to provide new insights into reliable biomarkers of osteosarcoma through the analysis of the functional single-nucleotide polymor-phisms of tumor-related genes.关键词
骨肉瘤/易感性/基因多态性/生物标志物/全基因组关联分析Key words
Osteosarcoma/Susceptibility/Single nucleotide polymorphisms/Biomarkers/Genome-wide asso-ciation study分类
医药卫生引用本文复制引用
张鹏,陈凯,黄玲玲,刘金燕,田文..骨肉瘤相关基因多态性的研究进展[J].肿瘤防治研究,2024,51(8):625-629,5.基金项目
Henan Province Science and Technology Research Projects(No.242102310351) （No.242102310351）
Henan Province Medical Science and Technology Research Plan Key Project of Provincial and Ministerial Cooperation(No.SBGJ202302021) 河南省科技攻关项目(242102310351) （No.SBGJ202302021）
河南省医学科技攻关计划省部共建重点项目(SBGJ202302021) （SBGJ202302021）
