用于小口径5 T磁共振成像系统的梯度线圈和1H/13C双共振射频线圈研制OACSTPCD
Development of Gradient Coils and 1H/13C Dual-resonance RF Coils for a Small-bore 5 T MRI System
基于自主研制的5 T磁共振成像系统和13C代谢磁共振成像研究需求,设计了一种小口径磁共振成像梯度线圈和1H/13C双共振射频线圈系统.其中梯度线圈设计采用有限差分流函数方法,射频线圈设计为马鞍线圈结合表面线圈的双共振方案.采用有限元方法对磁场分布进行了数值模拟分析,成功研制出一套用于小口径5T13C磁共振成像的梯度与射频线圈,并利用自主研制的5T磁共振成像系统平台验证了设计方案的可行性,经过实验测试采集到13C标记的尿素水模磁共振图像和小鼠头部1H磁共振图像,为后续开展基于动态核极化的13C磁共振代谢成像奠定了基础.
Based on the independently developed 5 T magnetic resonance imaging(MRI)system and research needs of 13C metabolic MRI,a gradient coil and 1H/13C dual resonance radiofrequency(RF)coil system for small-bore MRI were designed.The gradient coil was designed by using the finite-difference stream function method,and the RF coil was designed as a saddle coil combined with a surface coil in a dual-resonance scheme.Numerical simulation analysis of the magnetic field distribution was carried out by using the finite-element method,and a set of gradient and RF coils for small-bore 5 T 13C MRI was successfully developed.The feasibility of the design scheme was verified using a home-made 5 T MRI system,and the magnetic resonance images of 13C-labeled urea phantom and 1H magnetic resonance images of mice head were acquired by experimental tests,which lays a foundation for 13C metabolic MRI based on dynamic nuclear polarization in the future.
易鹏;刘朝阳;曹丽;黄臻;程鑫;王佳鑫;陈黎;陈方;鲍庆嘉;张志
武汉轻工大学电气与电子工程学院,湖北武汉 430023波谱与原子分子物理国家重点实验室,武汉磁共振中心(中国科学院精密测量科学与技术创新研究院),湖北武汉 430071||中国科学院大学,北京 100049波谱与原子分子物理国家重点实验室,武汉磁共振中心(中国科学院精密测量科学与技术创新研究院),湖北武汉 430071
物理学
高场磁共振成像13C代谢磁共振成像梯度线圈1H/13C双共振线圈马鞍线圈表面线圈
high-field MRI13C metabolic MRIgradient coil1H/13C dual resonance coilsaddle coilsurface coil
《波谱学杂志》 2024 (003)
245-256 / 12
国家重点研发计划项目(2023YFE0113300,2022YFF0707000);中国科学院磁共振技术联盟科研仪器设备研制项目(2021-GZL001);中国科学院基础与交叉前沿科研先导专项(XDB0540300);国家自然科学基金项目(22327901,81627901,22374158,22127801,21927801,12205352,22204168);中国科学院精密测量科学与技术创新研究院交叉培育项目(S21S4101);中国科学院科研仪器研制项目(YJKYYQ20190032).
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