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掌上型核磁共振控制台的设计与实现OACSTPCD

Design of the Handheld NMR Console

中文摘要英文摘要

常规的核磁共振仪器具有体积大,不易携带等缺点,限制了其在现场石油勘探、食品安全、环境污染、质检等领域的应用.为此,本文提出了一种掌上型核磁共振控制台设计方案,在一块可编程片上系统芯片Zynq-7000上,通过高级精简指令集计算机(Advanced RISC Machine,ARM)核构建、现场可编程门阵列(Field Programmable Gate Array,FPGA)逻辑设计和控制程序设计,完成了整个掌上型核磁共振控制台的设计与实现.全部设计完成后,在课题组自研的0.5T桌面式核磁共振系统上,进行了自由感应衰减(Free Induction Decay,FID)、自旋回波(Spin Echo,SE)和CPMG(Carr-Purcell-Meiboom-Gill)几个基本脉冲序列的测试,验证了其整体架构设计的正确性和各个模块之间的协调性.设计的核磁共振控制台长10.6 cm,宽6.0 cm,高1.9 cm,在缩小体积的同时,还提高了脉冲序列的实时性和控制台的稳定性,为进一步研制便携式核磁共振仪器奠定了基础.

Conventional nuclear magnetic resonance(NMR)instruments are large and difficult to carry,which limits their application in fields such as on-site petroleum exploration,food safety,environmental pollution,and quality control.To address this issue,this paper proposes a design of a handheld NMR console.By utilizing an advanced RISC machine(ARM)core construction,field programmable gate array(FPGA)logic design and control program design on a programmable system-on-chip Zynq-7000,the entire handheld NMR console was designed and implemented.After completing the entire design,several basic pulse sequences,including free induction decay(FID),spin echo(SE),and Carr-Purcell-Meiboom-Gill(CPMG),were tested on a 0.5 T desktop NMR system developed by our research group.The tests validated the correctness of the overall architecture design and the coordination among various modules.The designed NMR console is 10.6 cm long,6.0 cm wide,and 1.9 cm high,which significantly reduces the size while enhancing the real-time performance of pulse sequence and improving the stability of the console,laying a foundation for further development of portable NMR instruments.

李明道;姚守权;徐俊成;吕兴龙;何丰丞;蒋瑜

华东师范大学物理与电子科学学院,上海市磁共振重点实验室,上海 200062

物理学

核磁共振控制台现场可编程门阵列高级精简指令集计算机小型化

NMRconsoleFPGAadvanced RISC machineminiature

《波谱学杂志》 2024 (003)

257-265 / 9

上海市科技创新行动计划资助项目(19142202900);国家自然科学基金资助项目(21874045).

10.11938/cjmr20243108

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