波谱学杂志2024，Vol.41Issue(3)：276-285,10.DOI:10.11938/cjmr20243103
129Xe通气功能MRI与肺部病灶类型关联研究
Association of 129Xe Ventilation Functional MRI with Pulmonary Lesion Types
摘要
Abstract
This study investigates the correlation between 129Xe ventilation functional MRI and CT-detected pulmonary lesion types.We performed 129Xe ventilation functional MRI and CT scans on a sample of 143 patients,subsequently analyzing the relationship between lung ventilation function at the lobe level and CT lesion types.The findings suggest that the ventilation function from 129Xe MRI was consistent with CT results in the majority of lung lobes(74.6％).The ventilation function impairment of lung correlates with CT lesion types,particularly in instances of mixed diseases and emphysema/bullae,which are more prone to induce lung ventilation dysfunction.Moreover,distinct ventilation patterns are observed among different lesion types.That is,the data from both 129Xe ventilation functional MRI and CT provide complementary insights.The preliminary finding of this study offers data support for evaluating lung ventilation function caused by lung lesions,and provides more references for clinical imaging diagnosis,thereby contributing to the refinement of diagnostic and therapeutic strategies for pulmonary diseases.关键词
超极化129Xe/肺部通气功能磁共振成像/肺部CT/肺部疾病Key words
hyperpolarized 129Xe MRI/pulmonary ventilation functional MRI/lung CT/lung diseases分类
数理科学引用本文复制引用
陈琪,石磊,周倩,韩叶清,周欣,李海东,方媛,沈路阳,刘无己,罗明,李业成,张鸣,赵修超..129Xe通气功能MRI与肺部病灶类型关联研究[J].波谱学杂志,2024,41(3):276-285,10.基金项目
国家自然科学基金项目(82127802,21921004,82372150,82202119) （82127802,21921004,82372150,82202119）
国家重点研发计划项目(2018YFA0704000,2022YFC2410-000) （2018YFA0704000,2022YFC2410-000）
湖北省科技重大专项(2021ACA013,2023BAA021) （2021ACA013,2023BAA021）
中国科学院重点项目(ZDBS-LY-JSC004,XDB0540000) （ZDBS-LY-JSC004,XDB0540000）
中国科学院青年促进会项目(2020330,2021330). （2020330,2021330）
