磁共振成像2024，Vol.15Issue(7)：70-75,6.DOI:10.12015/issn.1674-8034.2024.07.012
颈动脉高分辨磁共振血管壁成像对缺血性脑卒中发生及复发诊断价值的Meta分析
Meta analysis of the diagnostic value of carotid artery high-resolution magnetic resonance vessel wall imaging in the occurrence and recurrence of ischemic stroke
摘要
Abstract
Objective:To analyze the diagnostic value of high-resolution magnetic resonance vascular wall imaging (HR-VWI) of the carotid artery for the occurrence and recurrence of ischemic stroke based on Meta. Materials and Methods:Retrieve relevant studies on HR-VWI assessment of ischemic stroke occurrence and recurrence published in Web of Science,Embase,The Cochrane Library,Medline,PubMed,China National Knowledge Network,Wanfang,and VIP database,with a search period from database establishment to February 2024. Select literature based on inclusion and exclusion criteria. Use a fixed effects model to calculate and combine the odds ratio (OR) or hazard ratio (HR) of different vulnerable carotid plaque features,and conduct meta-analysis using Stata 17.0 and RevMan 5.6. Results:Seventeen articles met the inclusion criteria. In 8 retrospective studies,intraplaque hemorrhage (OR=1.92,95％ CI:1.46-2.52),lipid-rich necrotic nucleus (OR=2.78,95％ CI:1.84-4.18),plaque calcification (OR=1.26,95％ CI:0.99-1.61) and fibrous cap rupture (OR=1.64,95％ CI:1.06-2.52) were significantly associated with ischemic stroke. In nine prospective studies,intraplaque hemorrhage (HR=6.88,95％ CI:4.46-10.61),lipid-rich necrotic nucleus (HR=1.78,95％ CI:0.87-3.65),fibrous cap rupture (HR=3.01,95％ CI:1.53-5.93) were significantly associated with ischemic stroke recurrence. Conclusions:HR-VWI can accurately evaluate the characteristics of carotid artery plaque components,which are significantly related with the occurrence and recurrence of ischemic stroke. Due to the lack of original research,a large sample size cohort study of carotid plaque is needed in the future to further provide timely accurate prediction of the occurrence and recurrence of ischemic stroke and guide clinical treatment by assessing the characteristics of carotid atherosclerotic plaque.关键词
脑卒中/卒中复发/磁共振成像/血管壁成像/颈动脉斑块/Meta分析Key words
stroke/stroke recurrence/magnetic resonance imaging/vascular wall imaging/vulnerable plaque/Meta analysis分类
临床医学引用本文复制引用
罗彤,高阳,吴琼,何金龙,王泽华..颈动脉高分辨磁共振血管壁成像对缺血性脑卒中发生及复发诊断价值的Meta分析[J].磁共振成像,2024,15(7):70-75,6.基金项目
内蒙古自治区自然科学基金项目(编号:2023QN08055) （编号:2023QN08055）
内蒙古自治区医疗卫生科技计划项目(编号:202201250) Natural Science Foundation of Inner Mongolia Autonomous Region(No.2023QN08055) （编号:202201250）
Healthcare and Technology Plan Project of Inner Mongolia Autonomous Region(No.202201250). （No.202201250）
