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3株鸡源沙门氏菌的耐药性和致病性分析

李若男 李杰峰 何欣 符乐 王珏 张宁 杨威 林向前 孙艳玲 赵兴华

动物医学进展2024,Vol.45Issue(9):32-38,7.
动物医学进展2024,Vol.45Issue(9):32-38,7.

3株鸡源沙门氏菌的耐药性和致病性分析

Drug Resistance and Pathogenicity Analysis of 3 Strains of Salmonella from Chickens

李若男 1李杰峰 2何欣 3符乐 2王珏 2张宁 2杨威 2林向前 2孙艳玲 3赵兴华3

作者信息

  • 1. 河北省畜牧兽医研究所,河北保定 071000||河北农业大学,河北保定 071000
  • 2. 河北省畜牧兽医研究所,河北保定 071000
  • 3. 河北农业大学,河北保定 071000
  • 折叠

摘要

Abstract

The aim of this study is identify suspected Salmonella isolated from three laying hen farms in Hebei province,China,Samples were subjected to biochemical identification,PCR identification,drug sensi-tivity testing,PCR identification of toxing genes,PCR identification of drug resistance genes,chicken path-ogenicity tests.The results showed that the resistance rate of the isolates to amoxicillin was up to 100%,and they were resistant to at least four antimicrobials simultaneously;The isolates carried a total of 8 kinds of drug resistance genes,among which the detection rates of floR,sul3 and blaOXA-1 were 100%;The isolates carried 10 kinds of virulence genes,among which the detection rates of sip A,sipC,invH,mgtC and stnP1 were the highest at 100%;There were deaths in all groups inoculated with the isolates,with the highest mortality of 80%in one group,indicates that the three Salmonella isolates have different pathoge-nicities.This study provides a reference for the clinical diagnosis and effective prevention of salmonellosis.

关键词

沙门氏菌/药物敏感性/耐药基因/毒力基因/致病性

Key words

Salmonella/drug sensitivity/drug resistance gene/virulence gene/pathogenicity

分类

农业科技

引用本文复制引用

李若男,李杰峰,何欣,符乐,王珏,张宁,杨威,林向前,孙艳玲,赵兴华..3株鸡源沙门氏菌的耐药性和致病性分析[J].动物医学进展,2024,45(9):32-38,7.

基金项目

农业基础性长期性科技工作动物疫病观测监测项目(NAES-AH-004) (NAES-AH-004)

动物医学进展

OA北大核心CSTPCD

1007-5038

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