MXene基复合材料在电化学生物传感器检测癌症标志物中的应用进展OA北大核心CSTPCD
Application of MXene-based Composites in Electrochemical Biosensors for Detection of Cancer Markers
癌症标志物的检测对于癌症的早期诊断、疗效监测和愈后具有重要意义.现有的传统检测方法存在一些局限性,特别是在癌症早期阶段通常难以及时准确地发现病变.电化学传感器作为一种高效的检测工具,能够满足多类癌症标志物的精准检测需求,为癌症患者的早期确诊提供了有力支持,具有广阔的应用前景.过渡金属碳/氮化物层状材料(MXene)是一种新兴的二维材料,具有高电子转移能力、高导电性、大的比表面积、良好的生物相容性和亲水性以及丰富的表面化学基团等独特的性能,被广泛应用于电化学传感器领域.本文综述了近年来基于MXene基复合材料的电化学生物传感器在癌症标志物检测中的应用进展,分析了MXene在电化学传感器中的作用,讨论了基于MXene的电化学传感器用于癌症早期诊断所面临的挑战和未来的发展趋势.
The detection of cancer markers is of great significance for the early diagnosis and subsequent treatment of cancer.However,the existing traditional detection methods have some limitations,especially in the early stages of cancer,thus is often difficult to detect in a timely and accurate manner.As an efficient detection technique,electrochemical sensors can meet the requirement of accurate detection of various cancer markers,provide strong support for early diagnosis of cancer,and have broad application prospects.MXene is a new two-dimensional material,which is widely used in electrochemical sensors because of its unique properties such as high electron transfer ability,high conductivity,large specific surface area,good biocompatibility and hydrophilicity and abundant surface chemical groups,etc.This paper reviewed the applications of electrochemical biosensors based on MXene composites in cancer marker detection in recent years,introduced the function of MXene in electrochemical biosensor,and discussed challenges and future development trends of MXene in the early diagnosis of cancer,aiming to provide reference for early detection of cancer.
霍朝晖;陈晓雯;张晓敏;黄晓霞;蓝婉莹;江琪
广东第二师范学院化学与材料科学学院,广州 510303||广东省普通高校先进材料与节能减排工程技术开发中心,广州 510303广东第二师范学院化学与材料科学学院,广州 510303
MXene基复合材料癌症标志物电化学生物传感器评述
MXene-based compositesCancer markersElectrochemical biosensorsReview
《分析化学》 2024 (008)
1051-1060 / 10
大学生创新创业训练计划项目(No.S202314278017)、2022年广东省普通高校特色创新项目(No.2022KTSCX090)和广东省普通高校重点科研项目(No.2021KCXTD086)资助. Supported by the Innovation and Entrepreneurship Training Project for College Students(No.S202314278017),the 2022 Guangdong Province General University Characteristic Innovation Project(No.2022KTSCX090)and the Key Scientific Research Projects of General Universities in Guangdong Province(No.2021KCXTD086).
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