分子影像学杂志2024，Vol.47Issue(8)：826-829,4.DOI:10.12122/j.issn.1674-4500.2024.08.08
嗜酸性筋膜炎的临床、影像特征及误诊
Clinical and imaging features and misdiagnosis of eosinophilic fasciitis
摘要
Abstract
Objective To analyze the clinical features,imaging manifestations and misdiagnosis causes of eosinophilic fasciitis(EF),and to strengthen the understandings of clinical features,diagnostic key points and differential diagnosis of EF.Methods A retrospective analysis was performed on eleven EF patients admitted to Department of Rheumatology and Immunology of the Second Affiliated Hospital of Anhui Medical University from October 2018 to March 2023,including seven males and four females,with the age of onset ranging from 16 to 71 years old,and their demographics,clinical manifestations,imaging examination,pathological data,and treatment were analyzed.Results Clinical manifestations included subcutaneous swelling/stiffness(90.9%),arthralgia/inflammation(63.6%),sticky sensation(63.6%),pigmentation(45.5%),Prayer hand(36.36%),gully sign(18.18%),myalgia and muscle weakness(9.09%),etc.Imaging examination of eleven patients showed muscle MRI examination of the affected myofascial thickening,and one case found abnormal signal of muscle involvement and biopsy pathology suggested muscle involvement.Full-thickness skin and muscle biopsies were performed in eleven patients,and fascial thickening with chronic inflammation,fibrinoid degeneration,lymphocytic or plasma cell infiltration was mostly seen in pathology,and eosinophilic infiltration was seen in seven cases.Among them,ten cases underwent bone marrow biopsy,and seven cases had eosinophilic myelogram,and no hematologic tumors were found.Conclusion Eosinophilic fasciitis is a rare connective tissue disease,with many similarities in clinical features,imaging and pathological manifestations,and it is easy to be misdiagnosed.In-depth understanding of clinical and imaging features,analysis of causes of misdiagnosis can avoid misdiagnosis and mistreatment.关键词
嗜酸性筋膜炎/临床表现/影像特征/病理/误诊Key words
eosinophilic fasciitis/clinical manifestations/imaging features/pathology/misdiagnosis引用本文复制引用
徐舟舟,赵红..嗜酸性筋膜炎的临床、影像特征及误诊[J].分子影像学杂志,2024,47(8):826-829,4.基金项目
安徽省卫生健康委员会基金(AHWJ2023BAb20009) （AHWJ2023BAb20009）
安徽医科大学第二附属医院转化医学研究所科研基金(2022ZHYJ11) （2022ZHYJ11）
