广东医学2024，Vol.45Issue(8)：946-950,5.DOI:10.13820/j.cnki.gdyx.20240588
红外热成像技术在股静脉血流缓慢大鼠模型中的成像表达特性及其临床应用价值
Imaging characteristics and clinical application value of infrared thermal imaging in a rat model of slow femoral venous blood flow
摘要
Abstract
Objective To explore the imaging characteristics and clinical application value of infrared thermal imaging in a rat model of slow femoral venous blood flow.Methods Twelve Sprague-Dawley rats were randomly divided into two groups:the epinephrine group(model group)and the saline group(control group).The model group received 1 mg/mL epinephrine injections,while the control group received an equal volume of saline,administered twice.Two hours after the first injection,the rats were made to swim in ice water for 5 minutes.Infrared thermal imaging was used to meas-ure the temperature of both sides of the femoral triangle region before and after modeling.Blood samples were collected from the abdominal aorta to test coagulation indicators and IL-6 levels,and the right femoral vein was subjected to patho-logical examination.Results In the model group,activated partial thromboplastin time(APTT)(P＜0.01)and throm-bin time(TT)(P＜0.01)were significantly shorter than those in the control group,and IL-6 levels were higher(P=0.02).Histological examination of femoral vein sections showed normal vascular morphology with no clear inflammation or thrombosis.The highest pre-modeling temperature in the femoral triangle region of the model group was(35.34±0.47)℃,and post-modeling was(36.57±0.94)℃,showing a statistically significant difference(P＜0.01).The post-modeling highest temperature in the model group was higher than that in the saline group(P＜0.01).Conclusion Infra-red thermal imaging of the rat model of slow femoral venous blood flow shows relatively high temperatures.With its non-invasive and radiation-free advantages,infrared thermal imaging can serve as an auxiliary diagnostic tool for slow blood flow conditions.关键词
血流缓慢/动物模型/红外热成像表达特性/血液高凝Key words
slow blood flow/animal model/IRTI expression characteristics/blood hypercoagulation分类
医药卫生引用本文复制引用
陈伟毅,张勇彬,苏佳琪,林伟国,阮薇,邓方阁..红外热成像技术在股静脉血流缓慢大鼠模型中的成像表达特性及其临床应用价值[J].广东医学,2024,45(8):946-950,5.基金项目
广东省自然科学基金项目(2020A1515011370) （2020A1515011370）
广州开发区创新领军人才项目(2022-L002) （2022-L002）
