LncRNA CASC2靶向调控miR-155-5p及其对HCC细胞恶性表型的影响OACSTPCD
LncRNA CASC2 targets the regulation of miR-155-5p and its impact on the malignant phenotype of HCC cells
目的:长链非编码RNA(long non-coding RNA,lncRNA)癌易感性候选基因 2(cancer susceptibility candidate gene 2,CASC2)在卵巢癌、肝细胞癌(hepatocellular carcinoma,HCC)等多种恶性肿瘤中发挥抑癌基因的作用,但其在HCC中的作用机制尚未完全清楚.本研究旨在分析CASC2在HCC组织中的表达及临床意义,并探讨CASC2对人肝癌细胞系Huh-7细胞恶性表型…查看全部>>
Objective:Long non-coding RNA(lncRNA)cancer susceptibility candidate gene 2(CASC2)functions as a tumor suppressor gene in various malignancies,including ovarian cancer and hepatocellular carcinoma(HCC).However,its mechanism in HCC remains unclear.This study aims to analyze the expression and clinical significance of CASC2 in HCC tissues,and to explore the effect of CASC2 on the malignant phenotype of Huh-7 cells and its possible mechanism. Methods:Real-time …查看全部>>
刘猛;张德志;朱少功;季节
郑州人民医院普通外科,郑州 450000郑州人民医院普通外科,郑州 450000郑州人民医院普通外科,郑州 450000郑州人民医院普通外科,郑州 450000
肝细胞癌癌易感候选基因2Huh-7细胞增殖凋亡
hepatocellular carcinomacancer susceptibility candidate gene 2Huh-7 cellsproliferationapoptosis
《临床与病理杂志》 2024 (5)
656-665,10
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