临床与病理杂志2024，Vol.44Issue(5)：703-712,10.DOI:10.11817/j.issn.2095-6959.2024.240006
Hippo信号通路相关microRNA在结直肠癌中的作用
Role of Hippo signaling pathway-related microRNAs in colorectal cancer
摘要
Abstract
Colorectal cancer(CRC)is one of the most common malignant tumors worldwide.Although significant breakthroughs have been made in CRC research,its specific pathogenesis remains unclear.The Hippo signaling pathway plays a crucial role in the pathogenesis of CRC,and microRNAs(miRNAs),acting as oncogenes or tumor suppressor genes,influence CRC cell proliferation,invasion,migration,glycolysis,angiogenesis,and drug resistance by regulating the Hippo signaling pathway.Understanding of the role,resistance mechanisms,and prognostic value of Hippo signaling pathway-related miRNAs in CRC is vital for further research into CRC pathology development of targeted therapies,and optimization of prognostic evaluations.关键词
结直肠癌/微RNA/Hippo信号通路Key words
colorectal cancer/microRNA/Hippo signaling pathway引用本文复制引用
章子怡,田广玉,邱志远..Hippo信号通路相关microRNA在结直肠癌中的作用[J].临床与病理杂志,2024,44(5):703-712,10.基金项目
江苏省自然科学基金(BK20161354) （BK20161354）
江苏省青年医学杰出人才基金(QNRC2016448) （QNRC2016448）
镇江市重点研发计划社会发展项目(SH2022055).This work was supported by Natural Science Foundation of Jiangsu Province(BK20161354),Young Medical Key Talents Foundation of Jiangsu Province(QNRC2016448),and the Zhenjiang Key Research and Development Plan for Social Development(SH2022055),China. （SH2022055）
