工业微生物2024，Vol.54Issue(4)：156-160,5.DOI:10.3969/j.issn.1001-6678.2024.04.044
副溶血弧菌OpaR转录调控元研究
Analysis of OpaR Transcription Regulon in Vibrio parahaemolyticus
摘要
Abstract
This article aims to investigate the transcriptional regulation mechanism of OpaR regulon under the biofilm formation condition.By comparing the transcriptome data of wild-type and opaR gene mutant strains,it was found that OpaR regulates the transcription of 2243 genes,of which 1164 were down-regulated and 1079 were up-regulated.The functional enrichment analysis displayed that these genes involved molecular function,cellular components,biological processes,and other aspects.The metabolic pathway analysis revealed that differentially expressed genes mainly involved cellular metabolic pathways and environmental information processing.In addition,multiple genes related to biofilm formation were screened from the data.These findings provided important information for understanding the molecular mechanisms by which OpaR regulates biofilm formation.关键词
副溶血弧菌/调控元/转录组/OpaRKey words
Vibrio parahaemolyticus/regulon/transcriptome/OpaR引用本文复制引用
仇越,薛星帆,张苗苗,陆仁飞,张义全,周敏..副溶血弧菌OpaR转录调控元研究[J].工业微生物,2024,54(4):156-160,5.基金项目
南通市卫生健康委员会科研课题(编号:QN2022044). （编号:QN2022044）
