慢性炎性脱髓鞘性多发性神经病的磁共振神经成像特征分析OACSTPCD

Objective To analyze the MRI features of chronic inflammatory demyelinating polyneuropathy(CIDP)and the diagnostic efficiency,and provide evidence for the diagnosis and treatment of related diseases.Methods Seventy-two patients with CIDP admitted to the Second Affiliated Hospital of Zhengzhou University from June 2022 to September 2023 were selected as the observation group,and 50 healthy people were selected as the control group.All subjects underwent magnetic resonance neuroimaging(MRN)with 3.0T MRI scanner to analyze the effect of MRN in diagnosis of CIDP(sensitivity,specificity,positive predictive value,negative predictive value,accuracy and misdiagnosis rate),and the brachial plexus(BP)and lumbosacral plexus(LSP)neurography of patients were compared,and the imaging characteristics and diagnostic value of MRN were analyzed.Results The sensitivity of MRN in diagnosing CIDP was 81.94%(59/72),the specificity was 82.00%(41/50),the positive predictive value was 86.76%(59/68),the negative predictive value was 82.00%(41/50),the accuracy rate was 81.97%(100/122),and the missed diagnosis rate was 18.06%(13/72).The MRN features of CIDP patients were mainly enhancement of postganglionic signal,enlargement of nerve root,enhancement of preganglionic nerve and postganglionic nerve in intervertebral foramen segment,and"sleeve sign".The brachial plexus of 43 patients(61.3%)and the LS plexus of 51 patients had plexus hypertrophy,including homogeneous hypertrophy and multifocal fusiform hypertrophy.The contrast enhancement of cauda equina in the observation group was significantly stronger than that in the control group(P<0.05).The LS nerve root of brachial artery in the observation group was significantly larger than that in the control group(P<0.05).Conclusion MRN can be used to evaluate the distribution and characteristics of peripheral nerves in patients with CIDP,which can reflect the patient's condition with high accuracy,and can assist in the diagnosis of disease and guide the treatment of patients.It has certain clinical application value.