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基于"肝-脑-目"轴探讨中医药论治干眼OACSTPCD

Treatment of dry eyes with Chinese Medicine based on "liver-brain-eye" axis

中文摘要英文摘要

"肝""脑""目"三者在生理及病理上相互联系,形成了"肝-脑-目"轴交互体系.其关系存在多向交互串扰,影响干眼的发生发展.应用脏腑辨证理论从生理和病理两个层面对"肝-脑-目"轴的内涵进行阐述,并提出"肝-脑-目"轴的 3 种失衡状态及其与干眼发病的关系,且肝、肾与目的关系为"肝-脑-目"轴理论之关键.提出清肝疏肝以畅"肝-脑-目"轴、益精生髓以充"肝-脑-目"轴、补肝肾阴以理"肝-脑-目"轴的中医药治疗干眼思路,以期为临床治疗干眼提供参考.

The"liver","brain",and"eye"are intimately connected both physiologically and pathologically,constituting an interactive system known as the"liver-brain-eye"axis.This axis exhibits multi-directional interactions and crosstalk,influencing the onset and progression of dry eyes.This paper employs the theory of pattern identification of zang-fu organs to expound on the connotations of the"liver-brain-eye"axis from both physiological and pathological perspectives.It proposes three states of disequilibrium within the"liver-brain-eye"axis and their associations with the pathogenesis of dry eyes,emphasizing that the relationship among the liver,kidney,and eyes is pivotal to the"liver-brain-eye"axis theory.To offer ideas to dry-eye treatment as clinical references,this paper introduces the concepts of Chinese medicine:clearing and soothing the liver to harmonize the"liver-brain-eye"axis,tonifying essence and generating marrow to replenish the"liver-brain-eye"axis,and nourishing liver and kidney yin to regulate the"liver-brain-eye"axis.

雷竣显;周派;彭俊;田赛男;彭清华

湖南中医药大学,湖南 长沙 410208湖南中医药大学,湖南 长沙 410208||湖南省中医药防治眼耳鼻咽喉疾病与视功能保护工程技术研究中心,湖南 长沙 410208

中医学

干眼"肝-脑-目"轴脏腑辨证肝肾阴虚清肝疏肝益精生髓补肝肾阴

dry eyes"liver-brain-eye"axispattern identification of zang-fu organsyin deficiency of the liver and kidneyclearing and soothing the livertonifying essence and generating marrownourishing liver and kidney yin

《湖南中医药大学学报》 2024 (007)

1308-1312 / 5

国家中医药管理局人才支持项目——岐黄学者(国中医药人教函[2022]6号);湖南省人才托举工程——年轻优秀科技人才培养计划项目(2023TJ-N25);湖南省科技厅临床创新引导项目(2021SK51402);湖南省教育厅科学研究项目(22C0191).

10.3969/j.issn.1674-070X.2024.07.024

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