湖南中医药大学学报2024，Vol.44Issue(7)：1346-1350,5.DOI:10.3969/j.issn.1674-070X.2024.07.030
栀子治疗肝脏疾病作用机制研究进展
Research progress on mechanism of Zhizi(Gardeniae Fructus)in treating liver diseases
摘要
Abstract
Liver diseases are widespread and seriously threaten the life and health of the Chinese people.Currently,the treatment of liver diseases still faces challenges of lack of specific drugs as well as adverse drug reactions.However,Chinese medicine has shown unique advantages in preventing and treating liver diseases,among which Zhizi(Gardeniae Fructus)and its active ingredients have significant efficacy in treating various types of liver diseases.Modern pharmacological studies have also shown that Zhizi(Gardeniae Fructus)exhibits anti-inflammatory,anti-thrombotic,anti-viral,anti-oxidation,regulating blood lipids and other effects,which can alleviate symptoms of multiple liver diseases such as non-alcoholic fatty liver disease,liver cirrhosis,liver injury,and liver cancer.This paper summarizes the recent research on the mechanism of action of Zhizi(Gardeniae Fructus)in various liver diseases,aiming to provide a reference for further research and clinical application of Zhizi(Gardeniae Fructus)in the prevention and treatment of liver diseases.关键词
栀子/栀子苷/肝损伤/肝纤维化/肝癌Key words
Zhizi(Gardeniae Fructus)/geniposide/liver injury/liver fibrosis/liver cancer分类
医药卫生引用本文复制引用
吴金鸿,欧阳林旗,欧阳婷,邓桂明..栀子治疗肝脏疾病作用机制研究进展[J].湖南中医药大学学报,2024,44(7):1346-1350,5.基金项目
湖南省中医药科研计划重点项目(No.2021016) （No.2021016）
湖南中医药大学科研基金项目(No.2019XJJJ02) （No.2019XJJJ02）
中药粉体与创新药物省部共建国家重点实验室培育基地开放基金资助项目(21PTKF1024) （21PTKF1024）
湖南省卫生健康委科研项目(D202302048806). （D202302048806）
