湖南中医药大学学报2024，Vol.44Issue(8)：1476-1483,8.DOI:10.3969/j.issn.1674-070X.2024.08.017
血脂边缘升高人群中医证候特征的回顾性研究
Retrospective study on TCM pattern characteristics of people with elevated blood lipid margins
摘要
Abstract
Objective To explore the core pathogenesis and TCM pattern characteristics in people with elevated blood lipid margins,and to provide reference for early prevention and treatment of dyslipidemia in TCM.Methods A total of 1 404 individuals with elevated blood lipid margins who met the inclusion and exclusion criteria from December 2018 to December 2020 were recruited,including 720 females and 684 males,aged between 28 and 65 years old.Information including gender,age,blood pressure,height,weight,body mass index,fasting blood glucose,blood uric acid,triglycerides,cholesterol,low-density lipoprotein,high-density lipoprotein,as well as other TCM symptoms and signs was collected to establish a database of abnormal blood lipid levels.Frequency statistics,factor analysis,and systematic clustering were employed to explore the core pathogenesis and pattern characteristics.Results The top five TCM symptoms and signs with the highest frequency were tidal fever due to warm dampness,dry mouth,clear urine,bitter taste,and obesity;seven common factors were extracted by factor analysis,namely,spleen deficiency with blood stasis pattern,damp heat damaging yin pattern,damp heat affecting the spleen pattern,damp heat with stomach retention pattern,spleen deficiency with phlegm dampness pattern,phlegm heat damaging yin pattern,and stomach heat with spleen deficiency pattern;systematic clustering was divided into six TCM patterns and one state,namely,phlegm dampness accumulating in the spleen pattern,damp heat in the large intestine pattern,qi-yin injury with blood stasis pattern,yang qi insufficiency pattern,spleen and stomach deficiency pattern,three jiao damp heat pattern,and obesity.Conclusion The pattern distribution in people with elevated blood lipid margins mainly includes phlegm dampness accumulating in the spleen pattern,damp heat in the large intestine pattern,qi-yin injury with blood stasis pattern,yang qi insufficiency pattern,spleen and stomach deficiency pattern,three jiao damp heat pattern,and their manifestation of physical obesity.关键词
血脂边缘升高/证候分布/频数统计/因子分析/系统聚类/中满内热/治未病Key words
elevated blood lipid margins/pattern distribution/frequency statistics/factor analysis/systematic clustering/middle jiao fullness and internal heat/preventing a disease before it arises分类
医药卫生引用本文复制引用
熊华忠,徐云龙,师雨晴,周航,王位,曲雪,王梓旭,任吉祥..血脂边缘升高人群中医证候特征的回顾性研究[J].湖南中医药大学学报,2024,44(8):1476-1483,8.基金项目
国家重点研发计划项目(2018YFC1704702) （2018YFC1704702）
全国名老中医药传承工作室项目(吉中医药发[2022]48号) （吉中医药发[2022]48号）
吉林省中医药科技项目(2023021). （2023021）
