临床肝胆病杂志2024，Vol.40Issue(8)：1525-1532,8.DOI:10.12449/JCH240804
中草药相关肝损伤的表型特征及毒理机制
Phenotypic characteristics and toxicological mechanisms of herb-induced liver injury
摘要
Abstract
In order to deal with the problem of the safety of Chinese herbal medicine in a scientific way and further meet the growing health needs of people,it is particularly important to deepen the research on herb-induced liver injury.This article elaborates on the phenotypic characteristics and toxicological mechanisms of herb-induced liver injury and emphasizes that it should not only rely on the previous knowledge of the toxicity of Chinese herbal medicine,but also understand the new types of idiosyncratic toxicity,indirect toxicity,and mixed toxicity,which provide a new perspective for understanding the toxicological mechanisms of herb-induced liver injury and are of great importance to investigate the phenotype and toxicological mechanism of herb-induced liver injury.关键词
中草药/化学性与药物性肝损伤/中药毒理学Key words
Drugs,Chinese Herbal/Chemical and Drug Induced Liver Injury/Toxicology of Chinese Materia Medica引用本文复制引用
何婷婷,柏兆方,王伽伯,肖小河..中草药相关肝损伤的表型特征及毒理机制[J].临床肝胆病杂志,2024,40(8):1525-1532,8.基金项目
国家自然科学基金(82074112) （82074112）
国家中医药管理局中医药创新团队及人才支持计划项目(ZYYCXTD-C-202005) （ZYYCXTD-C-202005）
国家自然科学基金联合基金重点项目(U23A20519) National Natural Science Foundation of China(82074112) （U23A20519）
Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(ZYYCXTD-C-202005) （ZYYCXTD-C-202005）
the Joint Funds of the National Natural Science Foundation of China(U23A20519) （U23A20519）
