临床肝胆病杂志2024，Vol.40Issue(8)：1533-1537,5.DOI:10.12449/JCH240805
中草药相关肝损伤的诊断:实践中的挑战
Diagnosis of herb-induced liver injury:Challenges in practice
摘要
Abstract
With the increasingly wide application of herbal medicines and dietary supplements worldwide,herb-induced liver injury(HILI)has become an important etiology of drug-induced liver injury.Due to the diverse manifestations of HILI,the difficulty in medical history collection,and the lack of specific biomarkers,how to identify suspected patients and make a correct diagnosis has become a major challenge in practice.Causality assessment is commonly used in the diagnosis of HILI,but there is still a lack of prospective cohort studies with a large sample size.In addition,further studies are needed to search for the specific biomarkers for the diagnosis of HILI.The diagnosis and differential diagnosis of HILI are challenging,and currently there is still no universally accepted uniform and standard method for the diagnosis of all-cause HILI.关键词
中草药/化学性与药物性肝损伤/诊断/因果关系评估/生物标志Key words
Drugs,Chinese Herbal/Chemical and Drug Induced Liver Injury/Diagnosis/Causality Assessment/Biomarkers引用本文复制引用
董一诺,支阳,唐洁婷,茅益民..中草药相关肝损伤的诊断:实践中的挑战[J].临床肝胆病杂志,2024,40(8):1533-1537,5.基金项目
国家重点研发计划(2022YFC35022101) （2022YFC35022101）
"十三五"国家科技重大专项(2017ZX09304016) （2017ZX09304016）
国家自然科学基金(81970513,82270619) National Key Research and Development Program of China(2022YFC35022101) （81970513,82270619）
National Science and Technology Major Project during the 13th Five Year Plan Period(2017ZX09304016) （2017ZX09304016）
National Natural Science Foundation of China(81970513,82270619) （81970513,82270619）
