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脂代谢重编程与原发性肝癌发生发展的关系

李飞燕 王明刚 毛德文 张日云 王娜 罗银冰 刘晓萍 林玉培

临床肝胆病杂志2024,Vol.40Issue(8):1688-1692,5.
临床肝胆病杂志2024,Vol.40Issue(8):1688-1692,5.DOI:10.12449/JCH240829

脂代谢重编程与原发性肝癌发生发展的关系

Association of lipid metabolism reprogramming with the development and progression of primary liver cancer

李飞燕 1王明刚 2毛德文 3张日云 1王娜 3罗银冰 1刘晓萍 1林玉培1

作者信息

  • 1. 广西中医药大学研究生院,南宁 530200
  • 2. 广西中医药大学第一附属医院 科研部,南宁 530023
  • 3. 广西中医药大学第一附属医院 肝病科,南宁 530023
  • 折叠

摘要

Abstract

Lipid metabolism,as the basis of life maintenance,is a prerequisite for cell survival,and lipid homeostasis can rapidly respond to metabolic changes in a coordinated manner.In cancers,there is an increase in lipid metabolism in cancer cells to meet the requirements for plasma membrane synthesis and energy production.Abnormal lipid metabolism plays an important role in the progression of primary liver cancer.This article reviews the association between abnormal lipid metabolism and primary liver cancer,in order to find targets for the prevention and treatment of primary liver cancer.

关键词

肝肿瘤/脂类代谢/代谢重编程

Key words

Liver Neoplasms/Lipid Metabolism/Metabolic Reprogramming

引用本文复制引用

李飞燕,王明刚,毛德文,张日云,王娜,罗银冰,刘晓萍,林玉培..脂代谢重编程与原发性肝癌发生发展的关系[J].临床肝胆病杂志,2024,40(8):1688-1692,5.

基金项目

国家自然科学基金(82274434,81960841,82060848) (82274434,81960841,82060848)

广西自然科学基金(2020GXNSFBA297115,2020GXNSFAA297070) (2020GXNSFBA297115,2020GXNSFAA297070)

广西中医药大学博士启动基金(2020BS026) (2020BS026)

广西中医药大学第一附属医院博士启动基金(2020BS003) (2020BS003)

广西研究生教育创新计划项目(YCSW2023378,YCBZ2023157,YCSW2023384) (YCSW2023378,YCBZ2023157,YCSW2023384)

广西中医药大学研究生教育创新计划项目(YCSY2022024) (YCSY2022024)

广西高校中青年教师科研基础能力提升项目(2022KY0284,2023KY0324) National Natural Science Foundation of China(82274434,81960841,82060848) (2022KY0284,2023KY0324)

Guangxi Natural Science Foundation(2020GXNSFBA297115,2020GXNSFAA297070) (2020GXNSFBA297115,2020GXNSFAA297070)

Doctoral Start-up Fund of Guangxi University of Chinese Medicine(2020BS026) (2020BS026)

The First Affiliated Hospital of Guangxi University of Chinese Medicine Doctoral Start-up Fund(2020BS003) (2020BS003)

Innovation Project of Guangxi Graduate Education(YCSW2023378,YCBZ2023157,YCSW2023384) (YCSW2023378,YCBZ2023157,YCSW2023384)

Innovation Project of Guangxi Graduate Education of GXUCM(YCSY2022024) (YCSY2022024)

Project on Enhancement of Basic Research Ability of Young and Middle-aged Teachers in Guangxi Universities and Colleges(2022KY0284,2023KY0324) (2022KY0284,2023KY0324)

临床肝胆病杂志

OA北大核心CSTPCD

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