临床肝胆病杂志2024，Vol.40Issue(8)：1704-1708,5.DOI:10.12449/JCH240832
中药活性成分调控糖代谢抗胆管癌的分子机制
Molecular mechanism of traditional Chinese medicine active components in regulating glucose metabolism against cholangiocarcinoma
摘要
Abstract
Cholangiocarcinoma is a highly heterogeneous tumor with an insidious onset,severe conditions,a high degree of malignancy,and an extremely poor prognosis.Glucose is a major energy source for the proliferation and metastasis of cholangiocarcinoma,and the glucose metabolism pathway of cholangiocarcinoma cells will be re-edited in the process of rapid proliferation to produce a large amount of energy for their own needs.Traditional Chinese medicine has unique advantages in the treatment of cholangiocarcinoma,and studies have shown that the active components of traditional Chinese medicine can inhibit the development and progression of cholangiocarcinoma by regulating glucose metabolism.This article reviews the characteristics of glucose metabolism in cholangiocarcinoma and the role of the active components of traditional Chinese medicine in regulating glucose metabolism against cholangiocarcinoma,in order to provide new ideas for the treatment of cholangiocarcinoma.关键词
胆管肿瘤/碳水化合物代谢/中药/药理作用分子作用机制(中药)Key words
Bile Duct Neoplasms/Carbohydrate Metabolism/Traditional Chinese Drugs/Molecular Mechanisms of Pharmacological Action(TCD)引用本文复制引用
赵方言,李姗,王祥麒,尹怡..中药活性成分调控糖代谢抗胆管癌的分子机制[J].临床肝胆病杂志,2024,40(8):1704-1708,5.基金项目
河南省中医药科学研究专项课题(2023ZY2110) （2023ZY2110）
河南省高等学校青年骨干教师资助项目(2021GGJS084) The Special Project for Scientific Research on Traditional Chinese Medicine in Henan Province(2023ZY2110) （2021GGJS084）
The Training Program for Young Scholars in Universities of Henan Province(2021GGJS084) （2021GGJS084）
